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Aggravated Airway Inflammation: Research on Genomics and Optimal Medical Care (AirGOs-medical)
The study is performed as a randomized double-blinded prospective controlled trial. A total of 72 adult Acetyl salicylic acid (ASA) -exacerbated respiratory disease (AERD) -patients with uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) will be recruited. Those negative to ASA-challenge test will not enter the Clinical Trial . All patients entering the Clinical Trial, have undergone earlier ethmoidal surgery (partial/total) and have not gained disease control. F-helicobacter antigen is tested and treatment is given if indicated. The patients are recruited at the Helsinki University Hospital (HUH). The study will be monitored by a professional monitor. Electronic CRF and paper/electronic patient questionnaires provided by HUS will be used (eCRF and patient questionnairea, Granitics).
Details
| Lead sponsor | Sanna Salmi |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 40 |
| Start date | Thu Jan 31 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Chronic Rhinosinusitis (Diagnosis)
Interventions
- Placebo Oral Tablet
- Acetyl Salicylic Acid
Countries
Finland