NCT03824379 is a Phase 2 clinical trial of Magnesium citrate in Diabetic Nephropathies, sponsored by Ain Shams University.

Who is sponsoring NCT03824379?

NCT03824379 is sponsored by Ain Shams University.

What drugs are being tested in NCT03824379?

Interventions in NCT03824379: Magnesium citrate, Antidiabetic.

What condition does NCT03824379 study?

NCT03824379 studies Diabetic Nephropathies.

Is NCT03824379 still recruiting?

NCT03824379 is currently completed. Last updated 12 January 2021.

Last reviewed 2021-01-12 · How we verify

NCT03824379

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Magnesium Supplementation in Diabetic Nephropathy

Completed Phase 2 Last updated 12 January 2021

What this trial tests

Phase 2 trial testing Magnesium citrate in Diabetic Nephropathies in 60 participants. Completed in 1 March 2020.

Timeline

1 June 2019

Primary endpoint
1 March 2020

1 March 2020

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	60
Start date	1 June 2019
Primary completion	1 March 2020
Estimated completion	1 March 2020
Sites	1 location across Egypt

Drugs / interventions tested

Magnesium citrate (MAGNESIUM CITRATE) — full drug profile →
Antidiabetic — full drug profile →

Conditions studied

Diabetic Nephropathies — all drugs for Diabetic Nephropathies →

Sponsor

Ain Shams University

Who can join

Adults 18 to 85, any sex, with Diabetic Nephropathies. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Higher prevalence of hypomagnesaemia in diabetic patients with nephropathy was compared to those without nephropathy. Serum magnesium levels were significantly inversely correlated with serum creatinine and U-A/C ratio, and positively correlated with glomerular filtration rate (GFR). Hence, Magnesium supplementation using magnesium salts could be a good approach to improve the cardiovascular complications, insulin resistance index, lipid profile and kidney function in diabetic nephropathy patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Diabetic kidney disease in type 2 diabetes: a review of pathogenic mechanisms, patient-related factors and therapeutic options.
Woodhams L, Sim TF, Chalmers L, Yeap B, et al · · 2021 · cited 9× · PMID 33976959 · DOI 10.7717/peerj.11070
Impact of magnesium supplementation on clinical outcome and disease progression of patients with diabetic nephropathy: a prospective randomized trial.
Halawa N, Elsaid TW, El Wakeel LM, Shawki MA. · · 2023 · cited 6× · PMID 38107482 · DOI 10.1177/20406223231214641

Verify or expand the search:

Other trials of Magnesium citrate

Trials testing the same drug.

NCT04930237 — RELISTOR's Effects on Opioid-Induced Constipation · withdrawn

Other recruiting trials for Diabetic Nephropathies

Currently open trials in the same condition.

NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting
NCT07187713 — ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases · Phase 4 · recruiting
NCT06778018 — Nutritional Outcomes of Lotus Seed (Nelumbo Nucifera) on Diabetic Sensorimotor Polyneuropathy · NA · recruiting
NCT06441591 — Clinical Outcome of Vinpocetine in Diabetic Nephropathy · Phase 2, PHASE3 · recruiting
NCT06431477 — Efficacy and Safety of Telmisartan Compared With Losartan · Phase 4 · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03824379 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 12 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03824379.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing