Last reviewed · How we verify
NCT03823885
ECigs, Inflammation and Oxidative Stress
NA trial testing e-cigarette in E-cigarettes, Oxidative Stress, Inflammation in 148 participants. Completed in 1 October 2023.
8 February 2023
Quick facts
| Lead sponsor | University of California, Los Angeles |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 148 |
| Start date | 8 February 2019 |
| Primary completion | 8 February 2023 |
| Estimated completion | 1 October 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- e-cigarette — full drug profile →
- empty (-cigarette sham control)
Conditions studied
- E-cigarettes, Oxidative Stress, Inflammation — all drugs for E-cigarettes, Oxidative Stress, Inflammation →
Sponsor
University of California, Los Angeles
Who can join
Adults 21 to 45, any sex, with E-cigarettes, Oxidative Stress, Inflammation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Randomized controlled trial of acute use of electronic cigarette effect on oxidative stress and inflammation.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Elevated Cellular Oxidative Stress in Circulating Immune Cells in Otherwise Healthy Young People Who Use Electronic Cigarettes in a Cross-Sectional Single-Center Study: Implications for Future Cardiovascular Risk.
Kelesidis T, Tran E, Arastoo S, Lakhani K, et al · · 2020 · cited 28× · PMID 32896211 · DOI 10.1161/jaha.120.016983 -
Association of 1 Vaping Session With Cellular Oxidative Stress in Otherwise Healthy Young People With No History of Smoking or Vaping: A Randomized Clinical Crossover Trial.
Kelesidis T, Tran E, Nguyen R, Zhang Y, et al · · 2021 · cited 15× · PMID 34369981 · DOI 10.1001/jamapediatrics.2021.2351
Verify or expand the search:
- PubMed search for NCT03823885
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of e-cigarette
Trials testing the same drug.
- NCT05525078 — Quit or Switch: E-cigarette Study · NA · completed
- NCT04175457 — The Acute Effects of E-cigarette Inhalation on Vascular Function, Microcirculation and Thrombosis · NA · completed
- NCT04210180 — Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction · Phase 2, PHASE3 · completed
Other University of California, Los Angeles trials
Trials by the same sponsor.
- NCT04846517 — rTMS for Aneroxia Nervosa in Youth · NA · not yet recruiting
- NCT06701760 — Sodium Lactate in Severe TBI · Phase 2 · not yet recruiting
- NCT04996667 — Effect of iNO in Patients With Submassive and Massive PE · Phase 2 · withdrawn
- NCT05067387 — Evaluation of Oral THC and CBD in Men and Women · Phase 1 · not yet recruiting
- NCT07534696 — Evaluation of Non-Invasive Pelvic Floor Neuromuscular Stimulation for Urinary Incontinence After Prostatectomy · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03823885 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Los Angeles
- Last refreshed: 4 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03823885.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing