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NCT03823443
COPD Exacerbation Blood and Urine Biomarkers Study
trial in Chronic Obstructive Pulmonary Disease in 7 participants. Terminated before completion.
22 August 2019
Quick facts
| Lead sponsor | Columbia University |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 7 |
| Start date | 7 June 2018 |
| Primary completion | 22 August 2019 |
| Estimated completion | 8 January 2021 |
| Sites | 1 location across United States |
Conditions studied
- Chronic Obstructive Pulmonary Disease — all drugs for Chronic Obstructive Pulmonary Disease →
- Acute Exacerbation Copd — all drugs for Acute Exacerbation Copd →
- Alpha-1 Anti-trypsin Deficiency — all drugs for Alpha-1 Anti-trypsin Deficiency →
Sponsor
Columbia University
Who can join
Adults 35 to 80, any sex, with Chronic Obstructive Pulmonary Disease or Acute Exacerbation Copd. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This will be a prospective study examining serum levels of MMP-13 and alpha-1 antitrypsin as well as other biomarkers as well as urine biomarkers of smoking status and collagen degradation in the COPD patient population. Serum and urine biomarkers at baseline and after COPD exacerbations will be assessed against change in lung function as measured by pulmonary function testing.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03823443
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03823443 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Columbia University
- Last refreshed: 4 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03823443.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing