NCT03823430 (CLAMP) is a clinical trial of Pupillometry in Brain Damage, sponsored by Association Pro-arte.

Who is sponsoring NCT03823430?

NCT03823430 is sponsored by Association Pro-arte.

What drugs are being tested in NCT03823430?

Interventions in NCT03823430: Pupillometry.

What condition does NCT03823430 study?

NCT03823430 studies Brain Damage, External Ventricular Drain, Hydrocephalus.

Is NCT03823430 still recruiting?

NCT03823430 is currently completed. Last updated 16 February 2022.

Last reviewed 2022-02-16 · How we verify

NCT03823430: CLAMP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pupillometry : Predictive Indicator in External Ventricular Drain Clamping ?

Completed Last updated 16 February 2022

What this trial tests

trial testing Pupillometry in Brain Damage in 100 participants. Completed in 11 March 2021.

Timeline

11 July 2018

Primary endpoint
2 January 2021

11 March 2021

Quick facts

Lead sponsor	Association Pro-arte
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	11 July 2018
Primary completion	2 January 2021
Estimated completion	11 March 2021
Sites	2 locations across France

Drugs / interventions tested

Pupillometry

Conditions studied

Brain Damage — all drugs for Brain Damage →
External Ventricular Drain — all drugs for External Ventricular Drain →
Hydrocephalus — all drugs for Hydrocephalus →

Sponsor

Association Pro-arte

Who can join

18 and older, any sex, with Brain Damage or External Ventricular Drain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Pupillar diameter variation to predict success or failure of external ventricular derivation clamping. Pupillometry utilisation as a diagnostic tool in external ventricular clamping test in neurological ICU should improve patients care in several ways : * earlier use of ventriculo-peritoneal or ventriculo-atrial shunts to shorten the external ventricular treatment duration and thus reduce risks of infection and hospital stay duration * limit the medical imagery prescription and radiation exposition * avoid neurological deterioration linked to the external ventricular drain clamping in case of the pupillometric parameters variation would be earlier than clinical signs

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Pupillometry

Trials testing the same drug.

NCT05829044 — Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms · NA · recruiting
NCT05962996 — Evaluation of Pain Levels by Quantitative Pupillometry During the Placement of Deep Venous Catheters in Sedated Patients · unknown
NCT04947397 — Investigation of Pupillometry as Guide for Extubation Readiness in Anesthetized Children · NA · completed
NCT04742790 — QSPainRelief-patientCNS : Clinical Biomarkers of Nociception, Sedation and Cognition · NA · unknown
NCT03862222 — Atlas of Retinal Imaging in Alzheimer's Study · completed

Other recruiting trials for Brain Damage

Currently open trials in the same condition.

NCT06027645 — Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder · NA · recruiting

Other Association Pro-arte trials

Trials by the same sponsor.

NCT03735693 — Diagnosis of Muscular Weakness Syndrome After a Stay in Intensive Care : Measurement by Ultrasound · terminated
NCT03836183 — Pleuropulmonary Ultrasound With Clinical Examination to Check the Good Position of the Double Lumen Tube Intubation · NA · completed
NCT03736239 — Ultrasound Study of the Diaphragm Evolution Under ECMO · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03823430 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Association Pro-arte
Last refreshed: 16 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03823430.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing