NCT03822026 is a NA clinical trial of Hyperventilation test in Head Injury Trauma, sponsored by University of Zurich.

Who is sponsoring NCT03822026?

NCT03822026 is sponsored by University of Zurich.

What drugs are being tested in NCT03822026?

Interventions in NCT03822026: Hyperventilation test.

What condition does NCT03822026 study?

NCT03822026 studies Head Injury Trauma, Hyperventilation.

Is NCT03822026 still recruiting?

NCT03822026 is currently completed. Last updated 30 January 2019.

Last reviewed 2019-01-30 · How we verify

NCT03822026

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hyperventilation in Patients With Traumatic Brain Injury

Completed NA Last updated 30 January 2019

What this trial tests

NA trial testing Hyperventilation test in Head Injury Trauma in 11 participants. Completed in 2 May 2017.

Timeline

20 May 2014

Primary endpoint
2 May 2017

2 May 2017

Quick facts

Lead sponsor	University of Zurich
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	11
Start date	20 May 2014
Primary completion	2 May 2017
Estimated completion	2 May 2017
Sites	1 location across Switzerland

Drugs / interventions tested

Hyperventilation test

Conditions studied

Head Injury Trauma — all drugs for Head Injury Trauma →
Hyperventilation — all drugs for Hyperventilation →

Sponsor

University of Zurich

Who can join

18 and older, any sex, with Head Injury Trauma or Hyperventilation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Elevated intracranial pressure is a dangerous and potentially fatal complication after traumatic brain injury. Hyperventilation is a medical intervention to reduce elevated intracranial pressure by inducing cerebral vasoconstriction, which might be associated to cerebral ischemia and hypoxia. The main hypothesis is that a moderate degree of hyperventilation is sufficient to reduce the intracranial pressure without inducing cerebral ischemia.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Cerebral metabolism is not affected by moderate hyperventilation in patients with traumatic brain injury.
Brandi G, Stocchetti N, Pagnamenta A, Stretti F, et al · · 2019 · cited 28× · PMID 30760295 · DOI 10.1186/s13054-018-2304-6
Transcranial color-coded duplex sonography assessment of cerebrovascular reactivity to carbon dioxide: an interventional study.
Klinzing S, Stretti F, Pagnamenta A, Bèchir M, et al · · 2021 · cited 3× · PMID 34364365 · DOI 10.1186/s12883-021-02310-9

Verify or expand the search:

Other trials of Hyperventilation test

Trials testing the same drug.

NCT03718780 — Assessment of Continuous Measurement of Transcutaneous CO2 for Evaluation of Alveolar Dead Space During Exercise · NA · unknown
NCT03810443 — Prevalence of the Hyperventilation Syndrome in Pulmonary Arterial Hypertension · NA · unknown

Other recruiting trials for Head Injury Trauma

Currently open trials in the same condition.

NCT06851234 — Osteopathic Manipulative Treatment RCT and Computational Modeling for Head Injuries in Mixed Martial Artists · NA · recruiting
NCT07339319 — Treatment and Outcome of Patients With Mild Head Injury · recruiting

Other University of Zurich trials

Trials by the same sponsor.

NCT07485699 — Soy Processing and Food Allergy · NA · not yet recruiting
NCT07516912 — Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland · not yet recruiting
NCT07473115 — Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustm · not yet recruiting
NCT07524023 — Emotional-distress-based Integrated Care Programme in Patients With Stable COPD · NA · recruiting
NCT06481982 — Value of Advanced MRI Techniques in the Assessment of Endometriosis · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03822026 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Zurich
Last refreshed: 30 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03822026.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing