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NCT03814850

Remote Ischemic PreConditioning (RIPC)

Withdrawn NA Last updated 8 December 2023
What this trial tests

NA trial testing Standard Manual Aneroid Sphygmomanometer in Unruptured Cerebral Aneurysm. Withdrawn.

Timeline
1 December 2024
Primary endpoint
31 December 2025
31 December 2025

Quick facts

Lead sponsorSebastian Koch
PhaseNA
StatusWithdrawn
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposesupportive care
Start date1 December 2024
Primary completion31 December 2025
Estimated completion31 December 2025
Sites2 locations across United States

Drugs / interventions tested

Conditions studied

Sponsor

Sebastian Koch

Who can join

18 and older, any sex, with Unruptured Cerebral Aneurysm. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to learn about protecting the brain from low blood flow (ischemia) with limb preconditioning. From human studies the investigators know that the brain can be protected from dangerous low blood flow by reducing the blood flow to an arm or leg for just a short period of time. This is called limb preconditioning. The investigators are studying the safety and feasibility of preconditioning and their effect of protecting the brain from ischemia in two different groups. This is a Phase 2, randomized, double-blind, sham-controlled, design. Up to 50 male and female patients undergoing elective endovascular repair of unruptured brain aneurysm who are randomized to the remote ischemic preconditioned or sham group will be enrolled. This study consists of one 3-9 month study period for each patient plus up to 14 days for enrollment activities. Subjects are required to return between 3-9 months for end-of-study procedures.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Remote ischaemic conditioning for stroke: unanswered questions and future directions.
    Baig S, Moyle B, Nair KPS, Redgrave J, et al · · 2021 · cited 15× · PMID 33903181 · DOI 10.1136/svn-2020-000722

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Other recruiting trials for Unruptured Cerebral Aneurysm

Currently open trials in the same condition.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03814850.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing