Who is sponsoring NCT03810378?

NCT03810378 is sponsored by Stanford University.

What drugs are being tested in NCT03810378?

Interventions in NCT03810378: Mediterranean Diet (Med-Plus), Well-Formulated Ketogenic Diet (WFKD).

What condition does NCT03810378 study?

NCT03810378 studies Diabetes Mellitus, Type 2, PreDiabetes.

Is NCT03810378 still recruiting?

NCT03810378 is currently completed. Last updated 21 February 2023.

Last reviewed 2023-02-21 · How we verify

NCT03810378

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial

Completed NA Last updated 21 February 2023

What this trial tests

NA trial testing Mediterranean Diet (Med-Plus) in Diabetes Mellitus, Type 2 in 61 participants. Completed in 6 December 2020.

Timeline

5 June 2019

Primary endpoint
4 December 2020

6 December 2020

Quick facts

Lead sponsor	Stanford University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	prevention
Enrollment	61
Start date	5 June 2019
Primary completion	4 December 2020
Estimated completion	6 December 2020
Sites	1 location across United States

Drugs / interventions tested

Mediterranean Diet (Med-Plus)
Well-Formulated Ketogenic Diet (WFKD)

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
PreDiabetes — all drugs for PreDiabetes →

Sponsor

Stanford University

Who can join

18 and older, any sex, with Diabetes Mellitus, Type 2 or PreDiabetes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study is to compare two metabolically distinct diets, WFKD vs Med-Plus, in order to examine the potential benefits, and unintended consequences, of going beyond a focus on maximally avoiding added sugars and refined grains, to also avoiding legumes, fruits, and whole grains.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effect of a ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2 diabetes mellitus: The interventional Keto-Med randomized crossover trial.
Gardner CD, Landry MJ, Perelman D, Petlura C, et al · · 2022 · cited 95× · PMID 35641199 · DOI 10.1093/ajcn/nqac154
Adherence to Ketogenic and Mediterranean Study Diets in a Crossover Trial: The Keto-Med Randomized Trial.
Landry MJ, Crimarco A, Perelman D, Durand LR, et al · · 2021 · cited 47× · PMID 33802709 · DOI 10.3390/nu13030967

Verify or expand the search:

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other Stanford University trials

Trials by the same sponsor.

NCT05945147 — Ketamine and Midazolam Infusions for CRPS: Feasibility Study · Phase 2 · withdrawn
NCT04225949 — Patients Understanding of PROM Graphs · NA · withdrawn
NCT06273098 — School-Based Bladder Health Intervention · NA · withdrawn
NCT04652635 — Management of Nailbed Injuries · NA · withdrawn
NCT05443503 — Stanford Spine Keeper - Managing Your Low Back Pain · NA · suspended

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03810378 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Stanford University
Last refreshed: 21 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03810378.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing