Who is sponsoring NCT03810157?

NCT03810157 is sponsored by Tang-Du Hospital.

What drugs are being tested in NCT03810157?

Interventions in NCT03810157: Laser-assisted hatching system.

What condition does NCT03810157 study?

NCT03810157 studies Pregnancy Outcomes.

Is NCT03810157 still recruiting?

NCT03810157 is currently status unknown. Last updated 25 June 2019.

Last reviewed 2019-06-25 · How we verify

NCT03810157

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Does LAH May Improve the Pregnancy Outcomes?

Status unknown NA Last updated 25 June 2019

What this trial tests

NA trial testing Laser-assisted hatching system in Pregnancy Outcomes in 1,200 participants. Status unknown.

Timeline

26 December 2018

Primary endpoint
1 October 2019

1 November 2019

Quick facts

Lead sponsor	Tang-Du Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	1,200
Start date	26 December 2018
Primary completion	1 October 2019
Estimated completion	1 November 2019
Sites	1 location across China

Drugs / interventions tested

Laser-assisted hatching system

Conditions studied

Pregnancy Outcomes — all drugs for Pregnancy Outcomes →

Sponsor

Tang-Du Hospital

Who can join

Adults 22 to 45, female only, with Pregnancy Outcomes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A defect in the hatching stage is considered an important cause of implantation failure. Therefore, assisted hatching (AH), which involves artificial disruption of the zona pellucida, has been proposed as a method for improving the capacity of the embryo to implant. But the advantage of using laser to facilitate the hatching process of embryos in ART practice is debatable, and an optimum strategy for performing LAH remains elusive. Therefore, the aim of this study was to evaluate the effects of laser-assisted hatching(LAH) on clinical outcomes. Patients were randomly divided into control and LAH groups. The zona pellucida was thinned or drilled with a diode laser. Relevant parameters are recorded to evaluate the validity of LAH in ART.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)).
Lacey L, Hassan S, Franik S, Seif MW, et al · · 2021 · cited 24× · PMID 33730422 · DOI 10.1002/14651858.cd001894.pub6

Verify or expand the search:

Other recruiting trials for Pregnancy Outcomes

Currently open trials in the same condition.

NCT07109544 — Effect of Breathing Exercises on Embryo Transfer Outcomes · NA · active not recruiting
NCT06234332 — Peking University Birth Cohort in Weifang (PKUBC-WF) · recruiting
NCT05403632 — Mediterranean Diet on Pregnancy and Foetus Development · recruiting
NCT05154331 — Antenatal and Postnatal Care Research Collective - Household Survey (ARCH) · recruiting
NCT04595760 — Factors Influencing Fertility or Pregnancy Health · active not recruiting

Other Tang-Du Hospital trials

Trials by the same sponsor.

NCT07528235 — An Open-Label, Dose-Escalation Study on the Safety, Tolerability and Preliminary Efficacy for Preventing SAP by Intraven · Phase 1 · not yet recruiting
NCT07516522 — Intra-arterial Methylprednisolone After Endovascular Thrombectomy · Phase 2 · recruiting
NCT07354061 — Neoadjuvant Therapy With Ensartinib Combined With Chemotherapy for ALK-positive Non - Small Cell Lung Cancer (NSCLC) · Phase 1, PHASE2 · recruiting
NCT07327736 — Anesthesia Comparison in Early-stage Small NSCLC: A Multicenter RCT · NA · not yet recruiting
NCT07452601 — Time-of-Day of Immunotherapy Infusion in Neoadjuvant Immunochemotherapy for Thoracic ESCC · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03810157 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tang-Du Hospital
Last refreshed: 25 June 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03810157.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing