NCT03806920 is a NA clinical trial of Intervention A in Diabetes Mellitus, Type 2, sponsored by German Institute of Human Nutrition.

Who is sponsoring NCT03806920?

NCT03806920 is sponsored by German Institute of Human Nutrition.

What drugs are being tested in NCT03806920?

Interventions in NCT03806920: Intervention A, Intervention B, Intervention C, Intervention D.

What condition does NCT03806920 study?

NCT03806920 studies Diabetes Mellitus, Type 2, Metabolic Syndrome.

Is NCT03806920 still recruiting?

NCT03806920 is currently completed. Last updated 24 June 2020.

Last reviewed 2020-06-24 · How we verify

NCT03806920

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Isomaltulose VS Sucrose - Postprandial Effect on Incretin Profile and Second Meal Effect

Completed NA Last updated 24 June 2020

What this trial tests

NA trial testing Intervention A in Diabetes Mellitus, Type 2 in 50 participants. Completed in 30 July 2019.

Timeline

5 November 2016

Primary endpoint
30 September 2018

30 July 2019

Quick facts

Lead sponsor	German Institute of Human Nutrition
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	prevention
Enrollment	50
Start date	5 November 2016
Primary completion	30 September 2018
Estimated completion	30 July 2019
Sites	1 location across Germany

Drugs / interventions tested

Intervention A — full drug profile →
Intervention B — full drug profile →
Intervention C — full drug profile →
Intervention D — full drug profile →

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
Metabolic Syndrome — all drugs for Metabolic Syndrome →

Sponsor

German Institute of Human Nutrition

Who can join

Adults 45 to 75, any sex, with Diabetes Mellitus, Type 2 or Metabolic Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study evaluates the different postprandial effect of isomaltulose and sucrose on the incretin profile and as an determinant for the second meal effect. In this nutritional intervention study, healthy participants and T2DM patients ingest 2 standardized meals for breakfast and lunch in combination with either sucrose or palatinose on 2 separate days. In addition, blood samples are taken to analyze markers of the carbohydrate metabolism, incretins and specific inflammation markers.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Implication of sugar, protein and incretins in excessive glucagon secretion in type 2 diabetes after mixed meals.
Zhang J, Schäfer SM, Kabisch S, Csanalosi M, et al · · 2023 · cited 5× · PMID 36857956 · DOI 10.1016/j.clnu.2023.02.011
Gut Hormones and Postprandial Metabolic Effects of Isomaltulose vs. Saccharose Consumption in People with Metabolic Syndrome.
Zhang J, Sonnenburg D, Kabisch S, Theis S, et al · · 2025 · PMID 40806123 · DOI 10.3390/nu17152539

Verify or expand the search:

Other trials of Intervention A

Trials testing the same drug.

NCT07009379 — Pillow Brace Assessment on Sleep Quality of Patients Undergoing Arthroscopic Rotator Cuff Surgery · NA · not yet recruiting

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other German Institute of Human Nutrition trials

Trials by the same sponsor.

NCT07505641 — Breathing and Decision-Making (ProlEx-Context) · NA · not yet recruiting
NCT07171281 — Precise Eating Time to Improve Glycemic Control and Cardiometabolic Health in Prediabetes and Diabetes · NA · recruiting
NCT06908447 — Cold Water and Decision-Making · NA · recruiting
NCT07133529 — Decision-making and Food Intake · NA · recruiting
NCT06515717 — Exogenous Ketones and Behavior · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03806920 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by German Institute of Human Nutrition
Last refreshed: 24 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03806920.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing