Last reviewed · How we verify
Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Oculocardiac reflex (OCR) is usually happening in pediatric strabismus surgery and observed just when the surgent pulls the ocular muscles. The reflex is one of the trigemino-vagal reflexes, and causes bradycardia, arrhythmia, and even cardiac arrest during eye surgery. Premedication for relaxation with drugs like hydroxyzine dihydrochloride or midazolam before surgery of the pediatric population is often used in Turkey, although it is not recommended in foreign countries. Some recent studies showed that when midazolam and hydroxyzine dihydrochloride used together not only, they lessen agitation before surgery but also they prevent emergence agitation. The primary aim of this prospective observational study is to show the effect of hydroxyzine dihydrochloride on preventing the pediatric patient from Oculocardiac reflex related to strabismus surgery.
Details
| Lead sponsor | Yeditepe University |
|---|---|
| Status | COMPLETED |
| Enrolment | 45 |
| Start date | Mon Oct 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Fri Feb 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Strabismus
- Reflex, Oculocardiac
- Hydroxyzine
- Bradycardia Sinus
Interventions
- Midazolam
- Hydroxyzine Dihydrochloride
Countries
Turkey (Türkiye)