NCT03803995 (MAP HIS HF) is a NA clinical trial of Mapping and Pacing the His Bundle in Heart Failure, sponsored by Abbott Medical Devices.

Who is sponsoring NCT03803995?

NCT03803995 is sponsored by Abbott Medical Devices.

What drugs are being tested in NCT03803995?

Interventions in NCT03803995: Mapping and Pacing the His Bundle, Placing a guidewire in Coronary sinus for measurement of Q-LV during His Bundle pacing or, if needed, for LV pacing.

What condition does NCT03803995 study?

NCT03803995 studies Heart Failure, Left Bundle-Branch Block.

Is NCT03803995 still recruiting?

NCT03803995 is currently completed. Last updated 2 October 2025.

Last reviewed 2025-10-02 · How we verify

NCT03803995: MAP HIS HF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Mapping and Pacing of the His Bundle for Heart Failure Patients With Left Bundle Branch Block

Completed NA Last updated 2 October 2025

What this trial tests

NA trial testing Mapping and Pacing the His Bundle in Heart Failure in 18 participants. Completed in 26 April 2024.

Timeline

20 March 2019

Primary endpoint
20 April 2024

26 April 2024

Quick facts

Lead sponsor	Abbott Medical Devices
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	18
Start date	20 March 2019
Primary completion	20 April 2024
Estimated completion	26 April 2024
Sites	1 location across United States

Drugs / interventions tested

Mapping and Pacing the His Bundle
Placing a guidewire in Coronary sinus for measurement of Q-LV during His Bundle pacing or, if needed, for LV pacing

Conditions studied

Heart Failure — all drugs for Heart Failure →
Left Bundle-Branch Block — all drugs for Left Bundle-Branch Block →

Sponsor

Abbott Medical Devices — full company profile →

Who can join

18 and older, any sex, with Heart Failure or Left Bundle-Branch Block. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective, single-arm, non-randomized, non-blinded study designed to characterize the locations of His Bundle (HB) pacing that results in correction of electrical dyssynchrony and to characterize morphology and activation time of local intracardiac electrogram (IEGM) with an electro-anatomical mapping system during a device implant procedure and secondarily to assess the efficacy of HB pacing or HB plus LV pacing (when indicated) in correction of electrical dyssynchrony in heart failure patients with left bundle branch block.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Is Conduction System Pacing a Valuable Alternative to Biventricular Pacing for Cardiac Resynchronization Therapy?
Castagno D, Zanon F, Pastore G, De Ferrari GM, et al · · 2024 · cited 2× · PMID 38786966 · DOI 10.3390/jcdd11050144

Verify or expand the search:

Other recruiting trials for Heart Failure

Currently open trials in the same condition.

NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting

Other Abbott Medical Devices trials

Trials by the same sponsor.

NCT07421076 — Grid eXplore Mapping Study · NA · recruiting
NCT07509658 — TriClip Japan Post-Approval Study · recruiting
NCT07361445 — Agilis RF TSP Early Feasibility Study · NA · recruiting
NCT07373353 — A Clinical Evaluation of AMJ-401 · NA · recruiting
NCT07217392 — Left Bundle Branch Area Pacing (LBBAP) PMCF Study · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03803995 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Abbott Medical Devices
Last refreshed: 2 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03803995.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing