NCT03803384 is a NA clinical trial of Oxygen therapy in COPD, sponsored by Schön Klinik Berchtesgadener Land.

Who is sponsoring NCT03803384?

NCT03803384 is sponsored by Schön Klinik Berchtesgadener Land.

What drugs are being tested in NCT03803384?

Interventions in NCT03803384: Oxygen therapy.

Is NCT03803384 still recruiting?

NCT03803384 is currently completed. Last updated 27 November 2019.

Last reviewed 2019-11-27 · How we verify

NCT03803384

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of an Auto-Regulating Oxygen System Compared to Constant-Flow Oxygen During Walking in Hypoxemic COPD Patients

Completed NA Last updated 27 November 2019

What this trial tests

NA trial testing Oxygen therapy in COPD in 55 participants. Completed in 26 November 2019.

Timeline

7 January 2019

Primary endpoint
26 November 2019

26 November 2019

Quick facts

Lead sponsor	Schön Klinik Berchtesgadener Land
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	55
Start date	7 January 2019
Primary completion	26 November 2019
Estimated completion	26 November 2019
Sites	1 location across Germany

Drugs / interventions tested

Oxygen therapy — full drug profile →

Conditions studied

COPD — all drugs for COPD →

Sponsor

Schön Klinik Berchtesgadener Land

Who can join

Adults 40 to 80, any sex, with COPD. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Oxygen therapy is a cornerstone in treating patients with severe chronic obstructive pulmonary disease. Usually, oxygen supplementation is delivered using constant-flow rates. Varying oxygenation levels may occur throughout patients´ changing activity. There is some evidence available that an auto-regulating oxygen flow system (FreeO2), which adjusts the oxygen flow automatically to prevent desoxygenation could be beneficial in comparison to a constant oxygen dose of 2 liter/min during walking. However, these possible benefits are unknown if the FreeO2 is compared to a constant oxygen dose according to the individual prescription. Therefore, the primary aim of this study is to investigate the effects of auto-regulated oxygen flow rates compared to constant oxygen flow rates as prescribed according to international guidelines on walking capacity in patients with COPD.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Automatic oxygen titration versus constant oxygen flow rates during walking in COPD: a randomised controlled, double-blind, crossover trial.
Schneeberger T, Jarosch I, Leitl D, Gloeckl R, et al · · 2023 · cited 20× · PMID 34656996 · DOI 10.1136/thoraxjnl-2020-216509
45. Jahrestagung der Österreichischen Gesellschaft für Pneumologie5. Jahrestagung der Österreichischen Gesellschaft für Thoraxchirurgie.
· 2021 · PMID 34611739 · DOI 10.1007/s00508-021-01942-8

Verify or expand the search:

Other trials of Oxygen therapy

Trials testing the same drug.

NCT07157696 — Advanced Respiratory Monitoring and Oxygen Therapy in Chronically Ill Patients With Acute Respiratory Failure · NA · not yet recruiting
NCT06776939 — Physiological Effect High-flow Tracheal Oxygen on Viscosity of Airway Mucus and Respiratory Effort in Patients Weaning f · NA · recruiting
NCT05511155 — Oxygen Therapy for Headache · completed
NCT04945564 — Covid-19 Patients Management During Home Isolation · NA · unknown
NCT04849598 — Automatic Oxygen Titration in Patients After SARS-CoV-2 Infection · NA · completed

Other recruiting trials for COPD

Currently open trials in the same condition.

NCT07344649 — Turkish Validation of the Nijmegen Questionnaire in COPD · recruiting
NCT07524023 — Emotional-distress-based Integrated Care Programme in Patients With Stable COPD · NA · recruiting
NCT07460154 — Structured Review: To Optimise Management and Prevent Harm in COPD · NA · recruiting
NCT07462221 — Effect of Telenursing on Oral Health · NA · recruiting
NCT07051707 — Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD · NA · recruiting

Other Schön Klinik Berchtesgadener Land trials

Trials by the same sponsor.

NCT07013903 — Effects of Hydrotherapy During Post-COVID-19 Rehabilitation · NA · recruiting
NCT06545851 — Effects of an Automatic Oxygen Titration System in People With Hypoxemia During Exercise Training · NA · recruiting
NCT05172206 — Symptom-based Rehabilitation Compared to Usual Care in Post-COVID - a Randomized Controlled Trial · NA · completed
NCT05124548 — Sleep Characteristics in Post-COVID-19 Patients · completed
NCT05126511 — Effects of Cranial Electrotherapy Stimulation on Anxiety of Patients After COVID-19 · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03803384 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Schön Klinik Berchtesgadener Land
Last refreshed: 27 November 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03803384.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing