NCT03801655 is a NA clinical trial of Bio-Kult in Mood, sponsored by University of Oxford.

Who is sponsoring NCT03801655?

NCT03801655 is sponsored by University of Oxford.

What drugs are being tested in NCT03801655?

Interventions in NCT03801655: Bio-Kult, Placebo.

What condition does NCT03801655 study?

NCT03801655 studies Mood, Cognitive Change.

Is NCT03801655 still recruiting?

NCT03801655 is currently status unknown. Last updated 11 January 2019.

Last reviewed 2019-01-11 · How we verify

NCT03801655

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

OxPALM: Oxford Study on Probiotics and Low Mood

Status unknown NA Last updated 11 January 2019

What this trial tests

NA trial testing Bio-Kult in Mood in 60 participants. Status unknown.

Timeline

15 August 2018

Primary endpoint
15 August 2020

15 August 2020

Quick facts

Lead sponsor	University of Oxford
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	other
Enrollment	60
Start date	15 August 2018
Primary completion	15 August 2020
Estimated completion	15 August 2020
Sites	1 location across United Kingdom

Drugs / interventions tested

Bio-Kult
Placebo

Conditions studied

Mood — all drugs for Mood →
Cognitive Change — all drugs for Cognitive Change →

Sponsor

University of Oxford

Who can join

Adults 18 to 55, any sex, with Mood or Cognitive Change. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Probiotics are live bacteria which have been suggested to have beneficial effects not only on gut function but also on psychological and cognitive functioning. This study will investigate how a specific probiotic influences emotional and cognitive processing in participants with low mood.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Multispecies probiotic administration reduces emotional salience and improves mood in subjects with moderate depression: a randomised, double-blind, placebo-controlled study.
Baião R, Capitão LP, Higgins C, Browning M, et al · · 2023 · cited 36× · PMID 35129111 · DOI 10.1017/s003329172100550x
Microbiome Modulators and Mood Disorders: Using a Multi-Strain Probiotic - Bio-Kult® Advanced - in Patients With Low Mood
Aswani D, Day R, Vijayakumar V, Naghibi M, et al · · 2022
Frequency of Diagnostic Classification Systems’ Usage by Mental Health Professionals in Day-to-Day Clinical Practice
Vrigkou E, Stamatakis R, Umla-Runge K. · · 2022
Psychiatric, Neurophysical and Neurocognitive Sequelae of Post-Acute COVID-19 Syndrome: A Systematic Review
Vincent A, Ofovwe O, Gschwandtner M, Shergill S, et al · · 2022

Verify or expand the search:

Other recruiting trials for Mood

Currently open trials in the same condition.

NCT07228013 — Examining Effects of Active Plant Engagement on College Student Well-Being and Performance · NA · active not recruiting
NCT07017023 — Combined Blood Pressure Medication and Activity Scheduling for Low Mood · EARLY_PHASE1 · recruiting
NCT07033052 — Developing Resilience and Anxiety Management Through the Arts · NA · recruiting
NCT06950424 — Effect of Black Cumin Seed Oil Supplementation on Cortisol, Stress and Mood · NA · active not recruiting
NCT06716554 — Efficacy and Safety of Shatavari for Treatment of Menopausal Symptoms in Women: A Randomized, Double-blind, Three-arm, P · NA · recruiting

Other University of Oxford trials

Trials by the same sponsor.

NCT05380388 — A Safety, Immunogenicity and Efficacy Study of PvRII/Matrix-M in Healthy Thai Adults Living in Thailand ( MIST3 ) · Phase 2 · not yet recruiting
NCT07470424 — A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults · Phase 1 · not yet recruiting
NCT07345910 — Environment, Pathogens, and Host Interactions in Melioidosis · not yet recruiting
NCT07434973 — Stratification and Treatment in Early Psychosis Study - PROMOTE · Phase 3 · not yet recruiting
NCT07460401 — 'Do Patient Characteristics Associate With Poor Outcome With Femoral Acetabular Impingement Syndrome (FAIS) Following Ph · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03801655 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Oxford
Last refreshed: 11 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03801655.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing