Who is sponsoring NCT03800641?

NCT03800641 is sponsored by Eye & ENT Hospital of Fudan University.

What condition does NCT03800641 study?

NCT03800641 studies Anxiety, Preoperative Care, Pharmacokinetics, Emergence Delirium.

What drugs are being tested in NCT03800641?

Interventions: Dexmedetomidine.

What is the status of NCT03800641?

NCT03800641 is currently COMPLETED.

Last reviewed 2022-01-11 · How we verify

A Study of Dexmedetomidine Pharmacokinetics for Preoperative Sedation

NCT03800641 PHASE4 COMPLETED

Proper preoperative sedation can reduce patients' anxiety, enhance patients' cooperation and reduce perioperative complications. The investigators would explore the sedative effects of dexmedetomidine (DEX) with the administration of oral, intravenous and nasal drops, and detect DEX blood concentration in 15 participants, respectively. Pharmacokinetic parameters are detected at 8 time points ( before DEX administration, 10 min, 20 min, 30 min, 45 min, 60min, 90min and 120 min after administration). 3 ml arterial blood was collected at each time point. The blood samples are detected by mass spectrometer. The aim of this study is to investigate appropriate administration time and route for DEX sedation.

Details

Lead sponsor	Eye & ENT Hospital of Fudan University
Phase	PHASE4
Status	COMPLETED
Enrolment	45
Start date	Fri Jan 11 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Jan 23 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Anxiety
Preoperative Care
Pharmacokinetics
Emergence Delirium

Interventions

Dexmedetomidine

Countries

China