NCT03792711 is a NA clinical trial of Ensure® Plus Advance in Frail Elderly Syndrome, sponsored by National Yang Ming Chiao Tung University.

Who is sponsoring NCT03792711?

NCT03792711 is sponsored by National Yang Ming Chiao Tung University.

What drugs are being tested in NCT03792711?

Interventions in NCT03792711: Ensure® Plus Advance.

What condition does NCT03792711 study?

NCT03792711 studies Frail Elderly Syndrome, Nutrition Disorders in Old Age, Muscle Loss.

Is NCT03792711 still recruiting?

NCT03792711 is currently completed. Last updated 11 April 2022.

Last reviewed 2022-04-11 · How we verify

NCT03792711

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effects of the Oral Nutritional Supplement With β-hydroxy-β-methylbutyrate in Lean Body Mass Among Taiwan Elderly

Completed NA Last updated 11 April 2022

What this trial tests

NA trial testing Ensure® Plus Advance in Frail Elderly Syndrome in 70 participants. Completed in 30 December 2020.

Timeline

18 February 2019

Primary endpoint
30 December 2020

30 December 2020

Quick facts

Lead sponsor	National Yang Ming Chiao Tung University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	70
Start date	18 February 2019
Primary completion	30 December 2020
Estimated completion	30 December 2020
Sites	1 location across Taiwan

Drugs / interventions tested

Ensure® Plus Advance

Conditions studied

Frail Elderly Syndrome — all drugs for Frail Elderly Syndrome →
Nutrition Disorders in Old Age — all drugs for Nutrition Disorders in Old Age →
Muscle Loss — all drugs for Muscle Loss →

Sponsor

National Yang Ming Chiao Tung University

Who can join

Adults 65 to 80, any sex, with Frail Elderly Syndrome or Nutrition Disorders in Old Age. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Primary objective: To evaluate the effects of additional oral nutritional supplement containing β-hydroxy-β-methylbutyrate (HMB) on thigh muscle mass in elderly subjects with pre-frail status Secondary objectives: 1. To evaluate the effects of additional oral nutritional supplement containing β-hydroxy-β-methylbutyrate on physical performance, nutrition status, and quality of life in elderly subjects with pre-frail status 2. To determine the safety profile of additional oral nutritional supplement containing β-hydroxy-β-methylbutyrate in elderly subjects with pre-frail status

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Oral Nutritional Supplement with β-hydroxy-β-methylbutyrate (HMB) Improves Nutrition, Physical Performance and Ameliorates Intramuscular Adiposity in Pre-Frail Older Adults: A Randomized Controlled Trial.
Peng LN, Cheng YC, Yu PC, Lee WJ, et al · · 2021 · cited 28× · PMID 34179932 · DOI 10.1007/s12603-021-1621-7
Dietary advice with or without oral nutritional supplements for disease-related malnutrition in adults.
Baldwin C, de van der Schueren MA, Kruizenga HM, Weekes CE. · · 2021 · cited 24× · PMID 34931696 · DOI 10.1002/14651858.cd002008.pub5

Verify or expand the search:

Other recruiting trials for Frail Elderly Syndrome

Currently open trials in the same condition.

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NCT06444321 — INTEgRated Health CARE for Patients With Frailty and Heart Failure · NA · recruiting
NCT05993754 — Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams · NA · recruiting
NCT06496022 — Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome · active not recruiting

Other National Yang Ming Chiao Tung University trials

Trials by the same sponsor.

NCT07448857 — Kinematics and Muscle Activation of Scapula in Upper String Players With Neck Pain · recruiting
NCT07318454 — Comparison of Abdominal Expansion and Abdominal Drawing-In Training With Manual and Verbal Cueing in Chronic Non-Specifi · NA · not yet recruiting
NCT07494461 — Inhibitory Control and Gait Adaptability in Parkinson's Disease · not yet recruiting
NCT07494487 — Reliability of Community Ambulation Ability, Fall Risk, and Dynamic Visual Acuity Assessments in Stroke · not yet recruiting
NCT07494500 — Vestibular Training on Community Ambulation and Fall Risk in Stroke · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03792711 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Yang Ming Chiao Tung University
Last refreshed: 11 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03792711.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing