NCT03791710

Effect of Autologous Fat Grafting on Acute Burn Wound Healing

Completed Phase 3 Last updated 10 July 2020

What this trial tests

Phase 3 trial testing autologous fat grafting in Burns in 100 participants. Completed in 31 January 2020.

Timeline

14 March 2019

Primary endpoint
31 January 2020

31 January 2020

Quick facts

Lead sponsor	Ahmed Mohamed Abouzaid
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	100
Start date	14 March 2019
Primary completion	31 January 2020
Estimated completion	31 January 2020
Sites	1 location across Egypt

Drugs / interventions tested

• autologous fat grafting
• Topical Cream
• split thickness skin grafting

Conditions studied

• Burns — all drugs for Burns →

Sponsor

Ahmed Mohamed Abouzaid

Who can join

Adults 13 to 60, any sex, with Burns. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

the study evaluates the role of autologous fat grafting and the usage of nanofat in the treatment of the acute burn injuries in different genders and its influences on the healing time and hospital stay, pain control, the need and take of a split thickness skin graft and its size, and the end resulting early scarring, in comparison with control group that were treated with traditional methods, so as to find out new method of treating burn injuries and decreasing its morbidity.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Adipose-derived stromal cells for nonhealing wounds: Emerging opportunities and challenges.
   Deptuła M, Brzezicka A, Skoniecka A, Zieliński J, et al · · 2021 · cited 38× · PMID 33522005 · DOI 10.1002/med.21789
2. Effect of autologous fat transfer in acute burn wound management: A randomized controlled study.
   Abouzaid AM, El Mokadem ME, Aboubakr AK, Kassem MA, et al · · 2022 · cited 25× · PMID 34906386 · DOI 10.1016/j.burns.2021.10.011