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NCT03790774
Neurofeedback in Alzheimer's Disease
NA trial testing Neurofeedback in Alzheimer Disease in 5 participants. Terminated before completion.
1 June 2020
Quick facts
| Lead sponsor | Oregon Health and Science University |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 5 |
| Start date | 6 June 2019 |
| Primary completion | 1 June 2020 |
| Estimated completion | 1 August 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Neurofeedback
Conditions studied
- Alzheimer Disease — all drugs for Alzheimer Disease →
Sponsor
Oregon Health and Science University
Who can join
Adults 50 to 100, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will evaluate behavioral and electrophysiological changes in a sample of adults with possible or probable Alzheimer's disease (AD), before and after undergoing training using a brain-computer interface (BCI) system with neurofeedback based on electroencephalography (EEG). Participants will repeatedly complete a letter viewing task and receive visual and auditory cues about their brainwaves. The study team hypothesizes that exposure to this EEG-based biofeedback intervention (neurofeedback) will result in a reduction of theta activity (brainwaves in the range of 4-8 Hz). The study team also predicts that exposure to the neurofeedback intervention will result in increased performance on reading, attention, and working memory tasks.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Brain-Computer Interfaces in Neurorecovery and Neurorehabilitation.
Young MJ, Lin DJ, Hochberg LR. · · 2021 · cited 35× · PMID 33742433 · DOI 10.1055/s-0041-1725137 -
Methodology and preliminary data on feasibility of a neurofeedback protocol to improve visual attention to letters in mild Alzheimer's disease.
Galvin-McLaughlin D, Klee D, Memmott T, Peters B, et al · · 2022 · cited 7× · PMID 35754975 · DOI 10.1016/j.conctc.2022.100950 -
Methodology and Preliminary Data on Feasibility of a Neurofeedback Protocol to Improve Visual Attention to Letters in Mild Alzheimer's Disease
Galvin-McLaughlin D, Klee D, Memmott T, Peters B, et al · · 2022 · DOI 10.2139/ssrn.4061360
Verify or expand the search:
- PubMed search for NCT03790774
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Neurofeedback
Trials testing the same drug.
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- NCT06240299 — Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR) · NA · recruiting
- NCT06188910 — Neurofeedback and Nomophobia in Young Adults · NA · completed
- NCT06557525 — Focused Research On Neurofeedback Therapy In Eradicating Depression (FRONTIER) · Phase 1, PHASE2 · recruiting
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Other Oregon Health and Science University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03790774 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oregon Health and Science University
- Last refreshed: 3 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03790774.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing