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NCT03790774

Neurofeedback in Alzheimer's Disease

Terminated NA Last updated 3 March 2021
What this trial tests

NA trial testing Neurofeedback in Alzheimer Disease in 5 participants. Terminated before completion.

Timeline
6 June 2019
Primary endpoint
1 June 2020
1 August 2020

Quick facts

Lead sponsorOregon Health and Science University
PhaseNA
StatusTerminated
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment5
Start date6 June 2019
Primary completion1 June 2020
Estimated completion1 August 2020
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Oregon Health and Science University

Who can join

Adults 50 to 100, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will evaluate behavioral and electrophysiological changes in a sample of adults with possible or probable Alzheimer's disease (AD), before and after undergoing training using a brain-computer interface (BCI) system with neurofeedback based on electroencephalography (EEG). Participants will repeatedly complete a letter viewing task and receive visual and auditory cues about their brainwaves. The study team hypothesizes that exposure to this EEG-based biofeedback intervention (neurofeedback) will result in a reduction of theta activity (brainwaves in the range of 4-8 Hz). The study team also predicts that exposure to the neurofeedback intervention will result in increased performance on reading, attention, and working memory tasks.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Brain-Computer Interfaces in Neurorecovery and Neurorehabilitation.
    Young MJ, Lin DJ, Hochberg LR. · · 2021 · cited 35× · PMID 33742433 · DOI 10.1055/s-0041-1725137
  2. Methodology and preliminary data on feasibility of a neurofeedback protocol to improve visual attention to letters in mild Alzheimer's disease.
    Galvin-McLaughlin D, Klee D, Memmott T, Peters B, et al · · 2022 · cited 7× · PMID 35754975 · DOI 10.1016/j.conctc.2022.100950
  3. Methodology and Preliminary Data on Feasibility of a Neurofeedback Protocol to Improve Visual Attention to Letters in Mild Alzheimer's Disease
    Galvin-McLaughlin D, Klee D, Memmott T, Peters B, et al · · 2022 · DOI 10.2139/ssrn.4061360

Verify or expand the search:

Other trials of Neurofeedback

Trials testing the same drug.

Other recruiting trials for Alzheimer Disease

Currently open trials in the same condition.

Other Oregon Health and Science University trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03790774.

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