NCT03790605 is a Phase 3 clinical trial of 1 % curcumin chip in Periodontitis, sponsored by KLE Society's Institute of Dental Sciences.

Who is sponsoring NCT03790605?

NCT03790605 is sponsored by KLE Society's Institute of Dental Sciences.

What drugs are being tested in NCT03790605?

Interventions in NCT03790605: 1 % curcumin chip, Placebo chip, Scaling and root planing.

What condition does NCT03790605 study?

NCT03790605 studies Periodontitis.

Is NCT03790605 still recruiting?

NCT03790605 is currently status unknown. Last updated 13 December 2019.

Last reviewed 2019-12-13 · How we verify

NCT03790605

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Clinical Trial to Study the Effect of a Drug, Curcumin in Patients With Periodontitis

Status unknown Phase 3 Last updated 13 December 2019

What this trial tests

Phase 3 trial testing 1 % curcumin chip in Periodontitis in 40 participants. Status unknown.

Timeline

4 September 2019

Primary endpoint
1 September 2020

1 December 2020

Quick facts

Lead sponsor	KLE Society's Institute of Dental Sciences
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	40
Start date	4 September 2019
Primary completion	1 September 2020
Estimated completion	1 December 2020
Sites	1 location across India

Drugs / interventions tested

1 % curcumin chip — full drug profile →
Placebo chip — full drug profile →
Scaling and root planing

Conditions studied

Periodontitis — all drugs for Periodontitis →

Sponsor

KLE Society's Institute of Dental Sciences

Who can join

Adults 20 to 60, any sex, with Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study will follow a parallel arm, randomised, double blinded, placebo controlled design. There will be two groups Group 1 = receiving 1% curcumin chips after routine scaling and root planing (n=20) Group 2 = receiving placebo chips after routine scaling and root planing (n=20) Clinical parameters: ( Baseline, 4 weeks, 12 weeks) Probing pocket depth, clinical attachment level, gingival index, plaque index Cytokine parameter ( Baseline, 4 weeks) Interleukin 1 beta in GCF Statistical analysis Repeated measures of ANOVA Paired t-tests

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

From Simple Mouth Cavities to Complex Oral Mucosal Disorders-Curcuminoids as a Promising Therapeutic Approach.
Girisa S, Kumar A, Rana V, Parama D, et al · · 2021 · cited 22× · PMID 33860191 · DOI 10.1021/acsptsci.1c00017
Pharmacological effects, formulations, and clinical research progress of curcumin.
Hao M, Zhang C, Wang T, Hu H. · · 2025 · cited 9× · PMID 40166470 · DOI 10.3389/fphar.2025.1509045

Verify or expand the search:

Other recruiting trials for Periodontitis

Currently open trials in the same condition.

NCT07463859 — Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabet · NA · recruiting
NCT07535177 — Gas6 and Soluble MerTK in Periodontal Diseases · recruiting
NCT07491848 — Oral-Periodontal Evaluation and Assessment of Oral Fluid Biomarkers in Patients With Hepatitis B+D · recruiting
NCT07421960 — Investigation of the Relationship Between Periodontitis and Sleep Quality · recruiting
NCT07532694 — Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients · NA · recruiting

Other KLE Society's Institute of Dental Sciences trials

Trials by the same sponsor.

NCT03044119 — The Effect of Platelet Rich Fibrin Matrix With and Without Peripheral Blood Mesenchymal Stem Cells on Implant Stability · Phase 1 · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03790605 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by KLE Society's Institute of Dental Sciences
Last refreshed: 13 December 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03790605.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing