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NCT03780868
External DCR Versus Canalicular SI With MMC in NLDO
NA trial testing external dacryocystorhinostomy in Primary Acquired Nasolacrimal Duct Obstruction in 56 participants. Completed in 31 July 2014.
1 July 2014
Quick facts
| Lead sponsor | Menoufia University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 56 |
| Start date | 1 June 2012 |
| Primary completion | 1 July 2014 |
| Estimated completion | 31 July 2014 |
Drugs / interventions tested
- external dacryocystorhinostomy
- canalicular silicone intubation with MMC
Conditions studied
- Primary Acquired Nasolacrimal Duct Obstruction — all drugs for Primary Acquired Nasolacrimal Duct Obstruction →
Sponsor
Menoufia University
Who can join
Adults 21 to 60, any sex, with Primary Acquired Nasolacrimal Duct Obstruction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
While external DCR is the gold standard procedure for primary NLDO as well as complicated cases, SI with MMC could achieve comparable success rates in primary acquired NLDO, hence should be considered as an alternative as a safe and minimally invasive procedure.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction.
Phelps PO, Abariga SA, Cowling BJ, Selva D, et al · · 2020 · cited 16× · PMID 32259290 · DOI 10.1002/14651858.cd012309.pub2
Verify or expand the search:
- PubMed search for NCT03780868
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Primary Acquired Nasolacrimal Duct Obstruction
Currently open trials in the same condition.
- NCT07154121 — Efficacy Evaluation of 5-Fluorouracil as an Adjuvant to Endoscopic Dacryocystorhinostomy in Managing Primary Acquired Na · NA · recruiting
Other Menoufia University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03780868 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Menoufia University
- Last refreshed: 19 December 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03780868.
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