Diagnostic Accuracy of the Central Venous Pressure (CVP) Variation to Predict Fluid Responsiveness in Spontaneously Breathing Patients (VPVC)

NCT03780660 COMPLETED

Volume expansion (VE) is often administered in intensive care (ICU)-patient to improve arterial oxygen delivery. Such effect is secondary to an increase in stroke volume and cardiac output. However, cardiac output increase in response to VE (fluid responsiveness) only occurs when the heart is preload-dependant. Increasing evidence of the deleterious effects of inappropriate fluid administration encourages the development of variables predicting fluid responsiveness, but few have been validated in spontaneously breathing patients. Central venous pressure (CVP) variation in spontaneously patients during standardized or unstandardized inspiratory maneuver may represent an easy tool to predict fluid responsiveness. The hypothesise is that inspiratory maneuver may increase CVP variation in fluid responsiveness patient whereas no or few variation may reflect fluid unresponsiveness.

Details

Lead sponsor	University Hospital, Lille
Status	COMPLETED
Enrolment	68
Start date	Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Wed Sep 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Breathing

Countries

France