NCT03769597 (DFG HEP) is a Phase 4 clinical trial of Iohexol Inj 300 MG/ML in Cirrhosis Renal, sponsored by University Hospital, Limoges.

Who is sponsoring NCT03769597?

NCT03769597 is sponsored by University Hospital, Limoges.

What drugs are being tested in NCT03769597?

Interventions in NCT03769597: Iohexol Inj 300 MG/ML.

What condition does NCT03769597 study?

NCT03769597 studies Cirrhosis Renal.

Is NCT03769597 still recruiting?

NCT03769597 is currently completed. Last updated 25 September 2019.

Last reviewed 2019-09-25 · How we verify

NCT03769597: DFG HEP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Description of the Evolution of Plasma and Urinary Concentrations of Iohexol in a Cirrhotic Patient Population

Completed Phase 4 Last updated 25 September 2019

What this trial tests

Phase 4 trial testing Iohexol Inj 300 MG/ML in Cirrhosis Renal in 13 participants. Completed in 28 August 2019.

Timeline

2 January 2019

Primary endpoint
28 August 2019

28 August 2019

Quick facts

Lead sponsor	University Hospital, Limoges
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	13
Start date	2 January 2019
Primary completion	28 August 2019
Estimated completion	28 August 2019
Sites	1 location across France

Drugs / interventions tested

Iohexol Inj 300 MG/ML — full drug profile →

Conditions studied

Cirrhosis Renal — all drugs for Cirrhosis Renal →

Sponsor

University Hospital, Limoges

Who can join

Adults 18 to 70, any sex, with Cirrhosis Renal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: It is important to accurately assess the glomerular filtration rate (GFR) of patients with liver diseases, particularly cirrhosis, to deliver care and adjust the drugs' posology. Purpose: The frequency of chronic renal failure is underestimated in patients with advanced liver disease and the difficulty to assess kidney failure justifies the investigator's study, which aims to describe, by means of a population pharmacokinetic model, the evolution of plasma and urinary concentrations of iohexol, an effective non-ionic, water-soluble contrast agent which is used in radiographic procedures, in cirrhotic patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Iohexol plasma and urinary concentrations in cirrhotic patients: A pilot study.
Carrier P, Destere A, Giguet B, Debette-Gratien M, et al · · 2022 · cited 4× · PMID 36157874 · DOI 10.4254/wjh.v14.i8.1621

Verify or expand the search:

Other trials of Iohexol Inj 300 MG/ML

Trials testing the same drug.

NCT05008276 — Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study) · recruiting
NCT03946345 — Iohexol for Measuring Renal Function · unknown
NCT03584217 — Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study · Phase 1, PHASE2 · unknown

Other University Hospital, Limoges trials

Trials by the same sponsor.

NCT07407101 — Impact of Filtration on Autologous Serum Eye Drops · NA · not yet recruiting
NCT07406425 — Evaluation of Efficacy of Coconut Oil Mouth Care for Non-autonomous Hospitalised Elderly People. · NA · not yet recruiting
NCT07436780 — B Lymphocyte Populations in the Pulmonary Microenvironment of Patients Under Mechanical Ventilation With or Without VAP · not yet recruiting
NCT07331298 — Apparent Diffusion Coefficient of the Intervertebral Disc in Children: Pilot Study · not yet recruiting
NCT07019818 — Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intu · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03769597 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Limoges
Last refreshed: 25 September 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03769597.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing