NCT03768193 (SAPB) is a NA clinical trial of Deep serratus anterior plane block in Thoracic Diseases, sponsored by Mater Misericordiae University Hospital.

Who is sponsoring NCT03768193?

NCT03768193 is sponsored by Mater Misericordiae University Hospital.

What drugs are being tested in NCT03768193?

Interventions in NCT03768193: Deep serratus anterior plane block, Surgically-placed paravertebral block.

What condition does NCT03768193 study?

NCT03768193 studies Thoracic Diseases, Thoracic Surgery, Rib Fractures, Pain, Postoperative, Pain, Procedural, Anaesthesia, Regional.

Is NCT03768193 still recruiting?

NCT03768193 is currently completed. Last updated 7 December 2018.

Last reviewed 2018-12-07 · How we verify

NCT03768193: SAPB

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery

Completed NA Last updated 7 December 2018

What this trial tests

NA trial testing Deep serratus anterior plane block in Thoracic Diseases in 40 participants. Completed in 1 September 2018.

Timeline

4 October 2017

Primary endpoint
1 September 2018

1 September 2018

Quick facts

Lead sponsor	Mater Misericordiae University Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	40
Start date	4 October 2017
Primary completion	1 September 2018
Estimated completion	1 September 2018
Sites	1 location across Ireland

Drugs / interventions tested

Deep serratus anterior plane block
Surgically-placed paravertebral block

Conditions studied

Thoracic Diseases — all drugs for Thoracic Diseases →
Thoracic Surgery — all drugs for Thoracic Surgery →
Rib Fractures — all drugs for Rib Fractures →
Pain, Postoperative — all drugs for Pain, Postoperative →

Sponsor

Mater Misericordiae University Hospital

Who can join

18 and older, any sex, with Thoracic Diseases or Thoracic Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Thoracic surgery, and surgery involving the chest wall in general, is associated with poorly controlled acute pain, which may result in delayed functional recovery, and may progress to chronic pain. Multimodal opioid-sparing analgesia regimens are a key component of the thoracic surgery enhanced recovery pathway, the aim of which is to improve outcomes in patients undergoing both minimally invasive and open thoracic surgical procedures. Novel interfascial plane blocks are emerging as feasible alternatives to central neuraxial analgesia techniques in a variety of clinical settings. The aim of this study is to show non-inferiority of serratus anterior blockade compared with surgically placed paravertebral blocks in the management of perioperative acute pain in patients undergoing VATS procedures.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Ultrasound-guided continuous deep serratus anterior plane block versus continuous thoracic paravertebral block for perioperative analgesia in videoscopic-assisted thoracic surgery.
Hanley C, Wall T, Bukowska I, Redmond K, et al · · 2020 · cited 59× · PMID 31955478 · DOI 10.1002/ejp.1533

Verify or expand the search:

Other trials of Deep serratus anterior plane block

Trials testing the same drug.

NCT04108715 — Erector Spina Plane Block Versus Deep Serratus Anterior Plane Block for Post Mastectomy Analgesia · NA · completed

Other recruiting trials for Thoracic Diseases

Currently open trials in the same condition.

NCT07250230 — Effect of Perioperative High-dose Transdermal Nicotine Patch on Pain Sensitivity Among Male Abstinent Tobacco Smokers Un · NA · recruiting
NCT05521789 — Erector Spinae Block for Thoracic Surgery · Phase 4 · recruiting
NCT04630496 — Geriatric Thoracic Surgery Ambulation Challenge · NA · recruiting

Other Mater Misericordiae University Hospital trials

Trials by the same sponsor.

NCT05642988 — Application of Wearable Technology in High-risk Surgical Patients in the Perioperative Period · completed
NCT05181371 — ESP Block in VATS: Programmed Intermittent Bolus Versus Continuous Infusion on Quality of Recovery · NA · completed
NCT04924010 — Effect of Perioperative CBT on Chronic Persistent Postsurgical Pain Among Breast Cancer Patients · NA · completed
NCT04729712 — Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery · NA · completed
NCT04370951 — Efficacy of the Erector Spinae Plane Block in Posterior Thoraco- Lumbar Spinal Decompression Surgery · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03768193 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mater Misericordiae University Hospital
Last refreshed: 7 December 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03768193.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing