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NCT03762343
Ultrasound-guided Greater Occipital Nerve Block in Children Undergoing Posterior Fossa Craniotomy
Phase 3 trial testing ultrasound guided Greater occipital nerve block in Posterior Fossa Tumor in 40 participants. Completed in 1 December 2020.
1 December 2020
Quick facts
| Lead sponsor | Kasr El Aini Hospital |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 January 2019 |
| Primary completion | 1 December 2020 |
| Estimated completion | 1 December 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- ultrasound guided Greater occipital nerve block — full drug profile →
- control group C — full drug profile →
Conditions studied
- Posterior Fossa Tumor — all drugs for Posterior Fossa Tumor →
Sponsor
Kasr El Aini Hospital
Who can join
Adults 2 to 10, any sex, with Posterior Fossa Tumor. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Surgery within the posterior fossa is associated with the highest incidence and greatest severity of acute postoperative pain that may persist beyond the immediate postoperative period. The utilization of local nerve blocks of the scalp in children may provide analgesia with stable hemodynamics while reducing the need for other anesthetics such as inhaled anesthetics and opioids. This could in turn result in less side effects, higher patient and family satisfaction, and better outcomes. The use of ultrasound-guided greater occipital nerve block (GONB) for perioperative pain management of posterior fossa surgery in pediatrics is not previously reported.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Intraoperative glioblastoma surgery-current challenges and clinical trials: An update.
Patel V, Chavda V. · · 2024 · cited 14× · PMID 39371095 · DOI 10.1016/j.cpt.2023.11.006
Verify or expand the search:
- PubMed search for NCT03762343
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Posterior Fossa Tumor
Currently open trials in the same condition.
- NCT06595667 — Fluid Responsiveness in Posterior Fossa Tumor Resection: PPV and CVP Guidance · NA · active not recruiting
- NCT06832384 — Intensive Physiotherapy in Children Affected by Posterior Fossa Tumors · recruiting
Other Kasr El Aini Hospital trials
Trials by the same sponsor.
- NCT07438652 — Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT · NA · recruiting
- NCT07488039 — Labroplasty in Cases of Anterior Shoulder Instability With Subcritical Glenoid Bone Loss · NA · recruiting
- NCT07274280 — Comparative Evaluation of Ambu AuraGain, LarySeal Pro and I-gel in Pediatric Airway Management for Day-Case Surgery Unde · NA · not yet recruiting
- NCT07348146 — Hand-Sewn vs. Stapled Anastomosis in SADI-S: Early Postoperative Complications. · NA · enrolling by invitation
- NCT07077265 — Comparing Two Different Norepinephrine Infusion Rates for Prophylaxis Against Spinal-induced Hypotension in Elderly · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03762343 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kasr El Aini Hospital
- Last refreshed: 15 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03762343.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing