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How Nicardipine and Labetalol Affect Cerebral Hemodynamics in Severe Preeclamptic Patients: A Pilot Observational Study (PREMODYM)
Realization of transcranial doppler and optic nerve sheath in severe preeclamptic patients to evaluate the impact of nicardipine and labetalol on cerebral hemodynamics.
Details
| Lead sponsor | Hopital Antoine Beclere |
|---|---|
| Status | UNKNOWN |
| Enrolment | 60 |
| Start date | 2018-11-29 |
| Completion | 2019-05 |
Conditions
- Preeclampsia Severe
Interventions
- optic nerve sheath measurement and transcranial doppler
Primary outcomes
- Change of values obtained by ultrasonography optic nerve sheath measurement from baseline to 2 hours post starting infusion of nicardipine or labetalol. — just before treatment and 2 hours after
Variation of values will be studied during a 2 hour time period, starting just before administration of either labetalol or nicardipine by i.v. route
Countries
France