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rTMS as an add-on Therapy in Patients With Post-stroke Depression
About 50% of all stroke patients develop post-stroke depression (PSD). A meta-analysis has shown that rTMS treatment can reduce depressive symptoms in PSD patients. In addition to rTMS alone for the improvement of depression, the question arises as to whether a combination therapy of rTMS plus antidepressant medication can achieve a stronger or longer-term effect in PSD patients. Unfortunately, there are currently no trials of combination therapy with rTMS and drug therapy in PSD patients. Therefore, this study will investigate whether combination therapy of antidepressant and rTMS can provide additional relief of depressive symptoms compared to antidepressant and sham rTMS therapy. It is assumed that the additional active rTMS achieves a faster normalization of affect and drive than with a sham rTMS, so that the patients benefit from neurorehabilitation measures earlier and more sustainably.
Details
| Lead sponsor | BDH-Klinik Hessisch Oldendorf |
|---|---|
| Phase | NA |
| Status | WITHDRAWN |
| Start date | Tue May 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Nov 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Post-stroke Depression
Interventions
- active rTMS
- sham rTMS
Countries
Germany