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NCT03760783
The Effects of Microgravity on Human Sperm
NA trial testing Parabolic flight in Semen Quality in 30 participants. Completed in 31 December 2021.
1 December 2021
Quick facts
| Lead sponsor | Fundacion Dexeus |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 30 |
| Start date | 20 November 2018 |
| Primary completion | 1 December 2021 |
| Estimated completion | 31 December 2021 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Parabolic flight
Conditions studied
- Semen Quality — all drugs for Semen Quality →
Sponsor
Fundacion Dexeus — full company profile →
Who can join
Adults 18 to 45, male only, with Semen Quality. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
It has been described that microgravity affects cellular and molecular structures. Cell membrane, cytoskeleton, cytoplasm and nucleus have been found to be sensible to gravitational changes. Alterations in the male and female reproductive systems have also been reported in mouse and other animals. The effects of microgravity on human reproductive cells remain unknown. The main objective of this experimental study is to investigate the effect of simulated microgravity in human male reproductive cells under in vitro conditions. Induced microgravity conditions will be obtained with a smaller single-engine aerobatic aircraft that can provide parabolic flights. The main parameters to be analyzed are: sperm motility, vitality, DNA fragmentation and apoptosis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Microgravity effects on frozen human sperm samples.
Boada M, Perez-Poch A, Ballester M, García-Monclús S, et al · · 2020 · cited 6× · PMID 32683528 · DOI 10.1007/s10815-020-01877-5
Verify or expand the search:
- PubMed search for NCT03760783
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Parabolic flight
Trials testing the same drug.
- NCT06736652 — Operational Performance Effects and Neurophysiology in Partial Gravity · NA · completed
Other Fundacion Dexeus trials
Trials by the same sponsor.
- NCT06763926 — Intranasal Nafarelin For Triggering Oocyte Maturation · Phase 4 · not yet recruiting
- NCT05836974 — Performance Evaluation of the ex Utero Cord Blood Collection Technique: Procedure, Quality and Results · NA · completed
- NCT04259021 — The Voice Analysis as a Preoperative Prediction Method of a Difficult Airway · completed
- NCT04108039 — Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles. · NA · completed
- NCT03740568 — Effect of Intervention on Progesterone Levels Before Euploid Embryo Transfer in Pregnancy Outcomes. · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03760783 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fundacion Dexeus
- Last refreshed: 31 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03760783.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing