NCT03758105 (DISCO) is a NA clinical trial of tDCS associated with usual care in Depression, sponsored by Nantes University Hospital.

Who is sponsoring NCT03758105?

NCT03758105 is sponsored by Nantes University Hospital.

What drugs are being tested in NCT03758105?

Interventions in NCT03758105: tDCS associated with usual care, Usual care.

What condition does NCT03758105 study?

NCT03758105 studies Depression.

Is NCT03758105 still recruiting?

NCT03758105 is currently status unknown. Last updated 27 February 2023.

Last reviewed 2023-02-27 · How we verify

NCT03758105: DISCO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure.

Status unknown NA Last updated 27 February 2023

What this trial tests

NA trial testing tDCS associated with usual care in Depression in 214 participants. Status unknown.

Timeline

4 February 2019

Primary endpoint
11 November 2023

11 November 2023

Quick facts

Lead sponsor	Nantes University Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	214
Start date	4 February 2019
Primary completion	11 November 2023
Estimated completion	11 November 2023
Sites	12 locations across France

Drugs / interventions tested

tDCS associated with usual care
Usual care

Conditions studied

Depression — all drugs for Depression →

Sponsor

Nantes University Hospital

Who can join

18 and older, any sex, with Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine the transcranial direct current stimulation (tDCS) cost-utility in the depression therapy. This is a 3 years medico-economics study with 1 year follow-up period involving patients with 1 or 2 depression treatment(s) failed. Eligible subject will be randomized in 2 groups, usual care with tDCS cure (arm A) or only usual care (arm B).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Cost-utility analysis of transcranial direct current stimulation (tDCS) in non-treatment-resistant depression: the DISCO randomised controlled study protocol.
Sauvaget A, Lagalice L, Schirr-Bonnans S, Volteau C, et al · · 2020 · cited 8× · PMID 31937653 · DOI 10.1136/bmjopen-2019-033376
Transcranial Direct Current Stimulation for Depression in Transgender Patient.
Sauvaget A, Bulteau S, Omon E, Ghazi E, et al · · 2023 · cited 1× · PMID 37273331 · DOI 10.7759/cureus.38476

Verify or expand the search:

Other recruiting trials for Depression

Currently open trials in the same condition.

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NCT07449676 — Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depression · NA · recruiting

Other Nantes University Hospital trials

Trials by the same sponsor.

NCT07278661 — Preoperative Use of Romiplostim in Thrombocytopenic Patients Undergoing Cardiac Surgery. · Phase 2 · recruiting
NCT06681363 — Creation of a Biocollection of Patients With Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelod · not yet recruiting
NCT07467382 — GOAT (Gait Observation of Achilles Tendon) · not yet recruiting
NCT07490379 — Comparison of the Efficacy of Transcranial Direct Current Stimulation at Home Versus in Hospital Settings in Patients Wi · NA · not yet recruiting
NCT07423481 — Weight Trajectories and Predictive Factors After Semaglutide in Patients With Grade 3 and Complicated Obesity · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03758105 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nantes University Hospital
Last refreshed: 27 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03758105.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing