Brain Imaging in the Diabetes Prevention Program Outcomes Study (DPPOS-Brain)

NCT03757910 EARLY_PHASE1 TERMINATED

This is a cross-sectional pilot study of Alzheimer's disease (AD) brain imaging biomarkers in Diabetes Prevention Program (DPP) outcomes study (DPPOS) participants from the New York City sites (Columbia and Einstein), comparing 10 persons originally randomized to metformin and 10 persons randomized to placebo in DPP. All study procedures will be conducted at Columbia University Irving Medical Center. Eligible participants will receive a PET scans and a brain MRI, which may be conducted in one, two, or three separate visits.

Details

Lead sponsor	José A. Luchsinger
Phase	EARLY_PHASE1
Status	TERMINATED
Enrolment	5
Start date	Tue Oct 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Tue Jan 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Alzheimer Disease

Interventions

• 18F-MK-6240
• 11C-PIB

Countries

United States