NCT03757429 (IMAR) is a clinical trial of RS-virus infection in Respiratory Tract Infections, sponsored by Uppsala University.

Who is sponsoring NCT03757429?

NCT03757429 is sponsored by Uppsala University.

What drugs are being tested in NCT03757429?

Interventions in NCT03757429: RS-virus infection.

What condition does NCT03757429 study?

NCT03757429 studies Respiratory Tract Infections, Respiratory Syncytial Virus Infections.

Is NCT03757429 still recruiting?

NCT03757429 is currently completed. Last updated 31 May 2022.

Last reviewed 2022-05-31 · How we verify

NCT03757429: IMAR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Inflammatory Mediators Associated With Infection by Respiratory Syncytial Virus

Completed Last updated 31 May 2022

What this trial tests

trial testing RS-virus infection in Respiratory Tract Infections in 31 participants. Completed in 1 April 2022.

Timeline

1 April 2018

Primary endpoint
1 April 2022

1 April 2022

Quick facts

Lead sponsor	Uppsala University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	31
Start date	1 April 2018
Primary completion	1 April 2022
Estimated completion	1 April 2022
Sites	1 location across Sweden

Drugs / interventions tested

RS-virus infection

Conditions studied

Respiratory Tract Infections — all drugs for Respiratory Tract Infections →
Respiratory Syncytial Virus Infections — all drugs for Respiratory Syncytial Virus Infections →

Sponsor

Uppsala University

Who can join

Eligibility, any sex, with Respiratory Tract Infections or Respiratory Syncytial Virus Infections. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Infection with human respiratory syncytial (RS) virus is the most common cause of hospital stay due to pediatric lower respiratory tract infection. An exaggerated immune response contributes to the pathogenesis and small children may have over reactive airways for a long time after an infection. New research has shown that polymorphonuclear leukocytes (PMNs) are stimulated by the virus. Besides fighting the infection they also cause collateral damage to the host. Among other mechanisms PMNs stimulates mucus formation that affects breathing. They also secrete enzymes, toxic proteins and free radicals that may cause harm to lung tissue and airways. The current project strives towards identifying and quantifying inflammatory mediators in sputum, urine and blood of children with severe RS-virus infection. The ultimate aim of the project is to, in detail, describe proteins contributing to the pathogenesis of the disease.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Respiratory Tract Infections

Currently open trials in the same condition.

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NCT06472219 — PREDICATE Trial For Respiratory Tract Infections · Phase 3 · recruiting
NCT05914324 — Outpatient Pediatric Pulse Oximeters in Africa · NA · recruiting
NCT06579170 — Burden of Recreational Water Illness Due to Exposure to Cyanobacteria and Their Toxins in Freshwater Beaches in Canada · active not recruiting

Other Uppsala University trials

Trials by the same sponsor.

NCT07517185 — The HIt HArd and hiT Early in Multiple Sclerosis Trial · Phase 2 · not yet recruiting
NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
NCT07461636 — Robotic-Assisted Pedicle Screw Placement in Spine Surgery · recruiting
NCT07273409 — Pancreatic Neuroendocrine Tumour - Optimal Surgical Debulking or Not · NA · recruiting
NCT07352683 — Open TAP-block in Pediatric Abdominal Surgery · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03757429 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Uppsala University
Last refreshed: 31 May 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03757429.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing