NCT03753178

Sensory Potentials and Ultrasonography in Common Peroneal Mononeuropathy

Completed Last updated 27 November 2018

What this trial tests

trial in Common Peroneal Neuropathy in 70 participants. Completed in 31 January 2016.

Timeline

1 January 2015

Primary endpoint
31 January 2016

31 January 2016

Quick facts

Lead sponsor	rania sanad
Status	Completed
Study type	OBSERVATIONAL
Enrollment	70
Start date	1 January 2015
Primary completion	31 January 2016
Estimated completion	31 January 2016

Conditions studied

• Common Peroneal Neuropathy — all drugs for Common Peroneal Neuropathy →

Sponsor

rania sanad

Who can join

Eligibility, any sex, with Common Peroneal Neuropathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Common peroneal mononeuropathy at the fibular neck (CPN) is one of the most frequent mononeuropathies of the lower extremities.

The common peroneal nerve sub serves sensation to the dorsum of the foot and toes. In CPN motor fibers of the deep peroneal nerve are more frequently affected than those of the superficial peroneal nerve. Fascicles of the deep branch of the common peroneal nerve are more anteriorly located and more vulnerable to injury than those of the superficial peroneal branch. The clinical and electrodiagnostic findings in CPN resemble the anatomical structure of the common peroneal nerve, indeed fibers for the deep peroneal nerve and the superficial peroneal nerve are bounded in separate fascicles along the course of the nerve.

Superficial peroneal nerve sensory potential (SPSP) should be performed to localize the site of injury.

Electrodiagnostic testing is used widely to evaluate the function of the common peroneal nerve. SPSP have been examined in CPN with conflicting results. A loss in amplitude of this response implies some axonal loss affecting either the common peroneal nerve or its superficial branch. Prominent axonal loss is the hallmark of most CPN lesions and suggested that abnormalities in sensory nerves mirror those in motor nerves.

Moreover, assessment of the structure of the common peroneal nerve is likely to improve the diagnostic yield" by using high-resolution ultrasonography. Ultrasound imaging is painless, does not expose the patient to radiation, and has several advantages compared with magnetic resonance imaging in the laboratory setting, including reduced cost, accessibility, ability to image the entire length of the nerve in a single study, and the ability to image both statically and dynamically.

This study was conducted to evaluate the superficial peroneal sensory potential and high-resolution ultrasonography role in confirmation of common peroneal mononeuropathy at the fibular neck.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.