NCT03747536 is a Phase 2 clinical trial of Ipratropium bromide in Sialorrhea, sponsored by London Health Sciences Centre.

Who is sponsoring NCT03747536?

NCT03747536 is sponsored by London Health Sciences Centre.

What drugs are being tested in NCT03747536?

Interventions in NCT03747536: Ipratropium bromide, Placebo.

What condition does NCT03747536 study?

NCT03747536 studies Sialorrhea.

Is NCT03747536 still recruiting?

NCT03747536 is currently status unknown. Last updated 21 November 2018.

Last reviewed 2018-11-21 · How we verify

NCT03747536

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ipratropium Bromide Spray as Treatment for Sialorrhea in Children

Status unknown Phase 2 Last updated 21 November 2018

What this trial tests

Phase 2 trial testing Ipratropium bromide in Sialorrhea in 30 participants. Status unknown.

Timeline

1 January 2019

Primary endpoint
1 October 2019

1 January 2021

Quick facts

Lead sponsor	London Health Sciences Centre
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	treatment
Enrollment	30
Start date	1 January 2019
Primary completion	1 October 2019
Estimated completion	1 January 2021

Drugs / interventions tested

Ipratropium bromide — full drug profile →
Placebo

Conditions studied

Sialorrhea — all drugs for Sialorrhea →

Sponsor

London Health Sciences Centre — full company profile →

Who can join

Adults 5 to 18, any sex, with Sialorrhea. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Double-blind, clinical trial investigating the effects of ipratropium spray versus placebo spray in children with sialorrhea

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Anticholinergic treatment for sialorrhea in children: A systematic review.
You P, Strychowsky J, Gandhi K, Chen BA. · · 2022 · cited 14× · PMID 35599670 · DOI 10.1093/pch/pxab051

Verify or expand the search:

Other recruiting trials for Sialorrhea

Currently open trials in the same condition.

NCT07516860 — Effect of SCS Technique on Oromotor Skills in Children With CP · NA · active not recruiting

Other London Health Sciences Centre trials

Trials by the same sponsor.

NCT04907071 — Intravascular Ultrasound for the Evaluation of Malperfusion Syndrome in the Setting of Acute Aortic Dissection · NA · completed
NCT04180553 — Ultrasound-Guided Resuscitation in Open Aortic Surgery · NA · unknown
NCT03216629 — Sorry Not Sorry: Apologizing and Its Effect on Discomfort During Dressing Removal · NA · completed
NCT03605030 — Reducing Radiation Exposure to Operators During Invasive Cardiac Procedures · NA · completed
NCT01087450 — The Effect of Erythropietin on Microcircualtory Alteration in Intensive Care Unit Patients With Severe Sepsis · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03747536 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by London Health Sciences Centre
Last refreshed: 21 November 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03747536.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing