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NCT03744897
Effect of Hypnosis Combined to Transcranial Direct Stimulation in Pain
NA trial testing Hypnotic analgesia in Pain Perception in 48 participants. Completed in 1 November 2018.
1 November 2018
Quick facts
| Lead sponsor | Hospital de Clinicas de Porto Alegre |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | other |
| Enrollment | 48 |
| Start date | 18 July 2017 |
| Primary completion | 1 November 2018 |
| Estimated completion | 1 November 2018 |
| Sites | 2 locations across Brazil |
Drugs / interventions tested
- Hypnotic analgesia
- a-tDCS
- Hypnotic analgesia + a-tDCS
- s-tDCS
Conditions studied
- Pain Perception — all drugs for Pain Perception →
- Pain Acute — all drugs for Pain Acute →
Sponsor
Hospital de Clinicas de Porto Alegre
Who can join
Adults 18 to 45, female only, with Pain Perception or Pain Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pain is a public health condition, which causes great functional disability. Its consequences pervade the personal and social life of the patient, leading to significant changes in their interpersonal relationships, including work, family and social spheres, reducing the ability to perform daily activities. Conventional treatment modalities have been show a very poor therapeutic response, in that most individuals end up becoming polymedicated patients and refractory to treatment. Among non-pharmacological techniques with promising analgesic effects it includes both the hypnotic analgesia and the transcranial stimulation of direct current (tDCS).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Comparison of Hypnotic Suggestion and Transcranial Direct-Current Stimulation Effects on Pain Perception and the Descending Pain Modulating System: A Crossover Randomized Clinical Trial.
Beltran Serrano G, Rodrigues LP, Schein B, Souza A, et al · · 2019 · cited 10× · PMID 31297046 · DOI 10.3389/fnins.2019.00662 -
The Hypnotic Analgesia Suggestion Mitigated the Effect of the Transcranial Direct Current Stimulation on the Descending Pain Modulatory System: A Proof of Concept Study.
Beltran Serrano G, Pooch Rodrigues L, Schein B, Zortea M, et al · · 2020 · cited 7× · PMID 32982393 · DOI 10.2147/jpr.s253747
Verify or expand the search:
- PubMed search for NCT03744897
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pain Perception
Currently open trials in the same condition.
- NCT07467551 — Turkish Validity and Reliability of the Behavioral Indicators of Pain Scale(ESCID) · NA · recruiting
- NCT07257432 — Electronic Anesthetic Efficacy Prof. Ali Rokia Ph.D. Al-Andalus University Prof . Mouetaz Kheirallah Ph.D ArabUST · NA · active not recruiting
- NCT06968325 — AI-Designed Clear Aligners: A Randomized Clinical Trial · NA · active not recruiting
- NCT06841601 — Effectiveness of Vibratory Versus Cold Stimuli on Pain Perception in Children · NA · recruiting
Other Hospital de Clinicas de Porto Alegre trials
Trials by the same sponsor.
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- NCT07052058 — Triple-Blind Randomized Clinical Trial of Tocilizumab vs Placebo: Potential Use of an IL-6 Antagonist as an Adjuvant to · Phase 2 · not yet recruiting
- NCT06953128 — General Versus Regional Anesthesia in Peripheral Arterial Surgery · NA · not yet recruiting
- NCT06934707 — Meal Frequency and Glycemic Control in Individuals With Type 1 Diabetes · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03744897 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital de Clinicas de Porto Alegre
- Last refreshed: 26 November 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03744897.
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