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Quantitative HPV Genotyping in Screening of Anal Intraepithelial Neoplasia in HIV-positive Patients (GAIN)
The pathophysiology from anal HPV infection to Anal Intraepithelial Neoplasia is less well understood than cervical HPV infection. In cervical screening programs it is well accepted that the sole presence of a high-risk HPV strain (irrespective of number of viral particles) is sufficient to justify further investigation and treatment. The investigators hypothesize that in anal HPV infection not only the presence but the extent of HPV infection (single genotype viral load) or combination of different HPV genotypes (cumulative viral load) is of importance in determining the risk of anal dysplasia.
Details
| Lead sponsor | Universitaire Ziekenhuizen KU Leuven |
|---|---|
| Phase | NA |
| Status | TERMINATED |
| Enrolment | 24 |
| Start date | Wed Aug 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Nov 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Human Immunodeficiency Virus
Interventions
- HPV genotyping
Countries
Belgium