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NCT03741283: OptiNAM
Optimisation of Nutrition and Medication for Acutely Admitted Older Medical Patients
NA trial testing Optimisation of nutrition and medication in Aging in 193 participants. Status unknown.
15 July 2022
Quick facts
| Lead sponsor | Hvidovre University Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 193 |
| Start date | 15 October 2018 |
| Primary completion | 15 July 2022 |
| Estimated completion | 15 July 2022 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Optimisation of nutrition and medication
Conditions studied
- Aging — all drugs for Aging →
- Malnutrition — all drugs for Malnutrition →
- Drug Prescribing — all drugs for Drug Prescribing →
Sponsor
Hvidovre University Hospital
Who can join
65 and older, any sex, with Aging or Malnutrition. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Malnutrition and inappropriate medication prescribing are highly prevalent among acutely admitted older medical patients leading to re-admissions, frailty, poor physical, performance compromised quality of life and mortality. Thus, the aim of this study is to optimise the nutrition and medication in older medical patients admitted to an acute care department at admission and up to 16 weeks after discharge. Participants in the intervention group receives a medication review and participants with malnutrition or risk of malnutrition additionally receive a transitional multimodal intervention. The control group receives standard care.
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
A Collaborative Medication Review Including Deprescribing for Older Patients in an Emergency Department: A Longitudinal Feasibility Study.
Houlind MB, Andersen AL, Treldal C, Jørgensen LM, et al · · 2020 · cited 34× · PMID 32012721 · DOI 10.3390/jcm9020348 -
Dietary advice with or without oral nutritional supplements for disease-related malnutrition in adults.
Baldwin C, de van der Schueren MA, Kruizenga HM, Weekes CE. · · 2021 · cited 24× · PMID 34931696 · DOI 10.1002/14651858.cd002008.pub5 -
Performance of Panel-Estimated GFR Among Hospitalized Older Adults.
Iversen E, Bengaard AK, Leegaard Andersen A, Tavenier J, et al · · 2023 · cited 18× · PMID 37516299 · DOI 10.1053/j.ajkd.2023.05.004 -
Effectiveness of a multidisciplinary and transitional nutritional intervention compared with standard care on health-related quality of life among acutely admitted medical patients aged ≥65 years with malnutrition or risk of malnutrition: A randomized controlled trial.
Andersen AL, Houlind MB, Nielsen RL, Jørgensen LM, et al · · 2024 · cited 5× · PMID 38777473 · DOI 10.1016/j.clnesp.2024.02.031 -
Patients' Attitudes Towards Deprescribing and Associations With Patient-Related Factors Across Two Hospital Settings.
Christensen LWS, El Gamah I, Barre AOI, Moga DC, et al · · 2026 · PMID 41742348 · DOI 10.1111/bcpt.70215 -
Plasma NGAL, suPAR, KIM-1 and GDF-15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients.
Houlind MB, Nielsen AL, Walls AB, Christensen LWS, et al · · 2025 · PMID 39865371 · DOI 10.1111/bcpt.70002
Verify or expand the search:
- PubMed search for NCT03741283
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03741283 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hvidovre University Hospital
- Last refreshed: 25 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03741283.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing