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Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy; a Randomized Controlled Trial (SUPE_R)
The purpose of this study is to improve early detection of treatable relapse of lung cancer and thereby improve survival and quality of life for the patients. The investigators will perform a multicenter, randomized controlled trial to 1) assess if surveillance with whole body Positron Emission Tomography combined with Computer Tomography (PET/CT) including the brain can increase the number of treatable relapses and 2) concurrently collect liquid biopsies for later analysis, potentially enabling even earlier and minimally invasive detection and characterization of relapse.
Details
| Lead sponsor | Rigshospitalet, Denmark |
|---|---|
| Phase | NA |
| Status | ACTIVE_NOT_RECRUITING |
| Enrolment | 750 |
| Start date | 2018-10-25 |
| Completion | 2026-08 |
Conditions
- Carcinoma, Non-Small-Cell Lung
Interventions
- Whole body 18F-FDG PET/CT
Primary outcomes
- Number of relapses treatable with curative intent — Until first detected relapse or 2 years after enrollment
As decided by multidisciplinary meetings
Countries
Denmark