Who is sponsoring NCT03739398?

NCT03739398 is sponsored by Yonsei University.

What drugs are being tested in NCT03739398?

Interventions in NCT03739398: LUTRONIC GENUS laser(Fractional Microneedle Radiofrequency(FMR)), LASEMED laser(The Thulium laser with 1,927nm wavelength).

Is NCT03739398 still recruiting?

NCT03739398 is currently completed. Last updated 29 September 2020.

Last reviewed 2020-09-29 · How we verify

NCT03739398

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Study on the Effectiveness and Safety Evaluation of Combination Therapy With 1,927nm Thulium Laser and Fractional Microneedle Radiofrequency Equipment for Improvement of Skin Aging

Completed NA Last updated 29 September 2020

What this trial tests

NA trial testing LUTRONIC GENUS laser(Fractional Microneedle Radiofrequency(FMR)) in Wrinkle in 26 participants. Completed in 23 April 2019.

Timeline

24 August 2018

Primary endpoint
23 April 2019

23 April 2019

Quick facts

Lead sponsor	Yonsei University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	26
Start date	24 August 2018
Primary completion	23 April 2019
Estimated completion	23 April 2019
Sites	1 location across South Korea

Drugs / interventions tested

LUTRONIC GENUS laser(Fractional Microneedle Radiofrequency(FMR))
LASEMED laser(The Thulium laser with 1,927nm wavelength)

Conditions studied

Wrinkle — all drugs for Wrinkle →

Sponsor

Yonsei University

Who can join

Adults 45 to 65, any sex, with Wrinkle. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Fractional Microneedle Radiofrequency (FMR) equipment is a device that penetrates the epidermis and irradiates the high frequency by entering the dermis. The generated radiofrequency transfers heat energy and induces thermal denaturation in the surrounding tissue.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Translation of Polymeric Microneedles for Treatment of Human Diseases: Recent Trends, Progress, and Challenges.
Yadav PR, Munni MN, Campbell L, Mostofa G, et al · · 2021 · cited 41× · PMID 34452093 · DOI 10.3390/pharmaceutics13081132
Clinical Measurement of Transepidermal Water Loss.
Kundu D, Jayaraman A, Sen CK. · · 2026 · cited 4× · PMID 40476522 · DOI 10.1089/wound.2024.0148

Verify or expand the search:

Other recruiting trials for Wrinkle

Currently open trials in the same condition.

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NCT06202274 — Clinical Study to Evaluate the Safety and Efficacy of Candela Technology · NA · active not recruiting

Other Yonsei University trials

Trials by the same sponsor.

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NCT07506629 — Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty · NA · not yet recruiting
NCT07515716 — Effects of High Flow Humidified Oxygen on Umbilical Artery Acid-base Balance in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
NCT07507188 — Collaborative Clinical-translational Cohort of Amivantamab Plus Lazertinib and Amivantamab Plus Chemotherapy in Patients · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03739398 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yonsei University
Last refreshed: 29 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03739398.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing