Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer

NCT03738969 UNKNOWN

This multi-center longitudinal study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between uterine cervical patients receiving different surgical routes (vaginal, laparotomy and laparoscopy), which is the primary study objective. All clinical and pathological data would be retracted from case reviews, and all survival data would be reached by clinic, telephone and mail follow-up. This study also would analyze the impact on survival outcomes of other factors, including nerve-sparing techniques, neoadjuvant chemotherapy, neoadjuvant radiotherapy and infection of human papillomavirus. The predictive effects of different following protocol and imaging plans will be also compared. Last, the influences of surgical routes on the fertility outcomes (pregnancy and its complications) and the ovarian reserve are important secondary study objectives.

Details

Lead sponsor	Lei Li
Status	UNKNOWN
Enrolment	3000
Start date	Sat Nov 10 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sat Dec 23 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Uterine Cervical Neoplasms
• Laparotomy
• Laparoscopy
• Survival
• Mortality
• Recurrence

Interventions

• Laparotomic radical hysterectomy
• Laparoscopic radical hysterectomy

Countries

China