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NCT03738826

Reducing Disparities in Medication Adherence in SLE

Completed NA Results posted Last updated 17 June 2025
What this trial tests

NA trial testing Behavioral Intervention in Systemic Lupus Erythematosus in 135 participants. Completed in 7 June 2020.

Timeline
2 October 2019
Primary endpoint
7 June 2020
7 June 2020

Quick facts

Lead sponsorDuke University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposehealth services research
Enrollment135
Start date2 October 2019
Primary completion7 June 2020
Estimated completion7 June 2020
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Duke University

Who can join

18 and older, any sex, with Systemic Lupus Erythematosus. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Feasibility as Measured by Number of Participants With EMR (Electronic Medical Record) Documentation of Adherence Primary · 12 weeks

Feasibility as measured by documentation of adherence assessment made by provider.

GroupValue95% CI
Behavioral Intervention116
Acceptability as Measured by Provider Survey Primary · 12 weeks

Acceptability as measured by provider survey, score range 1-5, with a higher score indicating that the intervention was more acceptable.

GroupValue95% CI
Lupus Clinic Providers4.4± 0.6
Percentage of Adherent Participants as Determined by Medication Possession Ratio (MPR) Secondary · Baseline, 12 weeks

Medication Possession Ratio (MPR) = days with medication/total days. This will be determined by pharmacy refill data and calculated for 3 months (90 days). An MPR \> or = 80% indicates adherence.

Baseline (prior to intervention)
GroupValue95% CI
Behavioral Intervention46
12 weeks (after intervention)
GroupValue95% CI
Behavioral Intervention55

Sponsor's own description

This is a pilot study to assess the feasibility of using Surescripts refill data during the clinical encounter to improve medication adherence in patients with systemic lupus erythematosus

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Pilot Intervention to Improve Medication Adherence Among Patients With Systemic Lupus Erythematosus Using Pharmacy Refill Data.
    Sun K, Eudy AM, Rogers JL, Criscione-Schreiber LG, et al · · 2023 · cited 6× · PMID 34739191 · DOI 10.1002/acr.24806

Verify or expand the search:

Other trials of Behavioral Intervention

Trials testing the same drug.

Other recruiting trials for Systemic Lupus Erythematosus

Currently open trials in the same condition.

Other Duke University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03738826.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing