Last reviewed · How we verify
NCT03737422
The Effects of Hesperidin and Flaxseed in Prediabetes
NA trial testing hesperidin and flaxseed in PreDiabetes in 48 participants. Completed in 1 December 2018.
1 October 2018
Quick facts
| Lead sponsor | National Nutrition and Food Technology Institute |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 48 |
| Start date | 1 January 2018 |
| Primary completion | 1 October 2018 |
| Estimated completion | 1 December 2018 |
| Sites | 1 location across Iran |
Drugs / interventions tested
- hesperidin and flaxseed
- control
Conditions studied
- PreDiabetes — all drugs for PreDiabetes →
Sponsor
National Nutrition and Food Technology Institute
Who can join
Adults 18 to 70, any sex, with PreDiabetes. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To study the effects of Hesperidin and flaxseed supplement in patients with prediabetes, 50 patients will be randomly allocated to control group or 2 capsules Hesperidin and 30 gram flaxseed for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, lipid profiles, blood pressure, blood sugar, inflammatory and anthropometric factors will be assessed and compared between groups.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Combination therapy of flaxseed and hesperidin enhances the effectiveness of lifestyle modification in cardiovascular risk control in prediabetes: a randomized controlled trial.
Yari Z, Naser-Nakhaee Z, Karimi-Shahrbabak E, Cheraghpour M, et al · · 2021 · cited 4× · PMID 33402222 · DOI 10.1186/s13098-020-00619-y
Verify or expand the search:
- PubMed search for NCT03737422
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of hesperidin and flaxseed
Trials testing the same drug.
- NCT03734835 — The Effect of Supplementation of Flaxseed, Hesperidin, Flaxseed and Hesperidin Together in Metabolic Syndrome · NA · unknown
- NCT03377153 — The Effects of Hesperidin and Flaxseed on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease · NA · unknown
Other recruiting trials for PreDiabetes
Currently open trials in the same condition.
- NCT06897982 — Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center · NA · recruiting
- NCT06967558 — The Role of Islet GLP-1 in the Pathogenesis of Prediabetes · Phase 2 · recruiting
- NCT06482944 — Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes · NA · recruiting
- NCT06989164 — Post Prandial Individual Responses to Different Foods · NA · recruiting
- NCT07254572 — Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes · Phase 4 · recruiting
Other National Nutrition and Food Technology Institute trials
Trials by the same sponsor.
- NCT06900946 — Evaluation of the Effects of Gluten Free Diet on Clinical Symptoms and Glycemic Index in Type 2 Diabetic Patients With N · NA · enrolling by invitation
- NCT06351696 — The Effects of Bromelain Supplement in Patients With Ulcerative Colitis · NA · recruiting
- NCT06353633 — The Effect of Exclusion Diet for Crohn's Disease Plus Enteral Nutrition on Children and Adolescents With Crohn's Disease · NA · not yet recruiting
- NCT06160830 — The Effects of Synbiotic on Cardiovascular and Bone Metabolism Markers in Transplanted Kidney Patients · NA · unknown
- NCT06096558 — The Effects of Melatonin on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03737422 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Nutrition and Food Technology Institute
- Last refreshed: 26 July 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03737422.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing