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NCT03735836

Effect of Fish Oil Monoglycerides on the Omega-3 Index

Completed Phase 4 Last updated 20 September 2019
What this trial tests

Phase 4 trial testing MAG-EPA/MAG-DHA omega-3 oils in Pharmacokinetic in Normal Population in 32 participants. Completed in 9 August 2019.

Timeline
8 August 2018
Primary endpoint
9 August 2019
9 August 2019

Quick facts

Lead sponsorSamuel Fortin
PhasePhase 4
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposebasic science
Enrollment32
Start date8 August 2018
Primary completion9 August 2019
Estimated completion9 August 2019
Sites2 locations across Canada

Drugs / interventions tested

Conditions studied

Sponsor

Samuel Fortin

Who can join

19 and older, any sex, with Pharmacokinetic in Normal Population. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study is to establish the pharmacokinetic curve for two different doses of MaxSimil at steady-state over a 20-week period, namely two (2) or three (3) tablets per day. MaxSimil is a concentrated fish oil monoglyceride (MAG) that facilitates absorption of the omega-3 oils by the body. Each capsule contains 300 mg of monoglyceride eicosapentaenoic acid (MAG-EPA) and 130 mg of monoglyceride docosahexaenoic acid (MAG-DHA). Thirty-two (32) subjects will be enrolled and randomly assigned to one of the two parallel treatment doses. Pharmacokinetics will be assessed by measuring the omega-3 index at eight (8) different times during the study. A first sample will be taken before the start of treatment and then every four (4) weeks during treatment. Then, two last measurements of the omega-3 index will be done at four (4) and seven (7) weeks after the end of treatment. Apart from the study treatment and collection of samples for the measurement of the omega-3 index, the only other interventions will be the measurement of body weight at screening and at the end of the study, pregnancy test for women at screening, questioning for demographic information and for the follow-up of the subject's health and concomitant medication intake.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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