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NCT03732092
The Effects of Olfactory Stimulation on Diagnosis and Prognosis of DOC Patients
trial testing Coma Recovery Scale-Revised in Minimally Conscious State in 20 participants. Completed in 15 December 2019.
15 November 2018
Quick facts
| Lead sponsor | Jing Wang |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 15 March 2018 |
| Primary completion | 15 November 2018 |
| Estimated completion | 15 December 2019 |
| Sites | 1 location across China |
Drugs / interventions tested
- Coma Recovery Scale-Revised
Conditions studied
- Minimally Conscious State — all drugs for Minimally Conscious State →
- Vegetative State — all drugs for Vegetative State →
Sponsor
Jing Wang
Who can join
Adults 18 to 65, any sex, with Minimally Conscious State or Vegetative State. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Analyze the behavioral response of patients with disorders of consciousness through olfactory stimulation, compare the response of olfactory stimulation in patients with different consciousness, and analyze the impact of olfactory stimulation on diagnosis; After the first, third, and sixth months of initial enrollment, the recovery of prognosis was tracked by the Coma Recovery Scale-Revision (CRS-R).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Olfactory Stimulation and the Diagnosis of Patients With Disorders of Consciousness: A Double-Blind, Randomized Clinical Trial.
Wang J, Zhang S, Liu W, Zhang Y, et al · · 2022 · cited 4× · PMID 35250440 · DOI 10.3389/fnins.2022.712891
Verify or expand the search:
- PubMed search for NCT03732092
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Coma Recovery Scale-Revised
Trials testing the same drug.
- NCT03549572 — Validity and Feasibility of the CRSR-FAST · completed
- NCT04471753 — Target Behaviours to Identify Minimally Conscious State Patients · completed
- NCT03508336 — The Initiation of Swallowing Can Indicate the Prognosis of DOC · completed
Other recruiting trials for Minimally Conscious State
Currently open trials in the same condition.
- NCT07456020 — Assessment of Consciousness With CRS-R and SECONDs · recruiting
- NCT06851156 — Transcranial Temporal Interference Stimulation In Severely Brain Injured Patients With Disorders of Consciousness · NA · recruiting
- NCT04065386 — Transcutaneous Auricular Vagal Nerve Stimulation for Post-coma Patients With Disorders of Consciousness · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03732092 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jing Wang
- Last refreshed: 29 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03732092.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing