NCT03731923

Abbreviated MRI for HCC Surveillance

Status unknown NA Last updated 18 August 2023

What this trial tests

NA trial testing Biannual ultrasonography in Hepatocellular Carcinoma in 257 participants. Status unknown.

Timeline

8 November 2018

Primary endpoint
15 December 2021

31 December 2023

Quick facts

Lead sponsor	Seoul National University Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	257
Start date	8 November 2018
Primary completion	15 December 2021
Estimated completion	31 December 2023
Sites	2 locations across South Korea

Drugs / interventions tested

• Biannual ultrasonography
• Annual abbreviated liver MRI

Conditions studied

• Hepatocellular Carcinoma — all drugs for Hepatocellular Carcinoma →
• Liver Cirrhosis — all drugs for Liver Cirrhosis →
• Chronic Hepatitis — all drugs for Chronic Hepatitis →

Sponsor

Seoul National University Hospital

Who can join

18 and older, any sex, with Hepatocellular Carcinoma or Liver Cirrhosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to investigate the clinical feasibility of abbreviated liver MRI for HCC surveillance in a high-risk group.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. British Society of Gastroenterology guidelines for the management of hepatocellular carcinoma in adults.
   Suddle A, Reeves H, Hubner R, Marshall A, et al · · 2024 · cited 41× · PMID 38627031 · DOI 10.1136/gutjnl-2023-331695
2. Role of imaging in management of hepatocellular carcinoma: surveillance, diagnosis, and treatment response.
   Osho A, Rich NE, Singal AG. · · 2020 · cited 33× · PMID 32944652 · DOI 10.20517/2394-5079.2020.42
3. Emerging Tools for Hepatocellular Carcinoma Surveillance.
   Singal AG, Reig M, Villanueva A. · · 2022 · cited 21× · PMID 36114768 · DOI 10.14309/ajg.0000000000002015
4. Current Landscape and Future Perspectives of Abbreviated MRI for Hepatocellular Carcinoma Surveillance.
   Park HJ, Seo N, Kim SY. · · 2022 · cited 19× · PMID 35434979 · DOI 10.3348/kjr.2021.0896
5. Imaging Modalities for Hepatocellular Carcinoma Surveillance: Expanding Horizons beyond Ultrasound.
   Park HJ, Kim SY. · · 2020 · cited 9× · PMID 37384318 · DOI 10.17998/jlc.20.2.99
6. Recent advances and issues in imaging modalities for hepatocellular carcinoma surveillance.
   Lee DH. · · 2025 · cited 5× · PMID 40007309 · DOI 10.17998/jlc.2025.02.16
7. Persisting challenges in the early detection of hepatocellular carcinoma.
   Arvind A, Redmon K, Singal AG. · · 2025 · cited 3× · PMID 39943795 · DOI 10.1080/14737140.2025.2467184
8. Abbreviated MRI-Based Surveillance Strategies for Early Hepatocellular Carcinoma Detection.
   Park HJ, Kim DW, Choi WM, Kim SY. · · 2025 · cited 1× · PMID 40502477 · DOI 10.3348/jksr.2024.0153