Last reviewed · How we verify
Proteomic Profiling of Coronary Thrombus in Acute Myocardial Infarction
ST-elevation myocardial infarction (STEMI) is mostly caused by the rupture or the erosion of a vulnerable atherosclerotic plaque, initiating with intraluminal thrombosis and resulting in total occlusion of the coronary artery. Thrombus formation is a complex and dynamic process involving flow, blood cells and several plasma proteins, and it has not been clearly elucidated. To define - through proteomic approach - the composition of occluding thrombus and its time changes in patients with STEMI, trying to identify novel biomarkers of coronary thrombosis.
Details
| Lead sponsor | G. d'Annunzio University |
|---|---|
| Status | UNKNOWN |
| Enrolment | 50 |
| Start date | Sun Jan 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Dec 31 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Acute Myocardial Infarction
- STEMI - ST Elevation Myocardial Infarction
Interventions
- Time from the onset of symptoms to PCI
Countries
Italy