NCT03730350 is a NA clinical trial of Clinical Hypnosis in Post-Surgical Pain, sponsored by University Health Network, Toronto.

Who is sponsoring NCT03730350?

NCT03730350 is sponsored by University Health Network, Toronto.

What drugs are being tested in NCT03730350?

Interventions in NCT03730350: Clinical Hypnosis.

What condition does NCT03730350 study?

NCT03730350 studies Post-Surgical Pain.

Is NCT03730350 still recruiting?

NCT03730350 is currently completed. Last updated 7 December 2020.

Last reviewed 2020-12-07 · How we verify

NCT03730350

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Perioperative ACT-Based Clinical Hypnosis for Opioid Weaning

Completed NA Last updated 7 December 2020

What this trial tests

NA trial testing Clinical Hypnosis in Post-Surgical Pain in 92 participants. Completed in 30 May 2020.

Timeline

15 November 2018

Primary endpoint
10 December 2019

30 May 2020

Quick facts

Lead sponsor	University Health Network, Toronto
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	92
Start date	15 November 2018
Primary completion	10 December 2019
Estimated completion	30 May 2020
Sites	1 location across Canada

Drugs / interventions tested

Clinical Hypnosis

Conditions studied

Post-Surgical Pain — all drugs for Post-Surgical Pain →

Sponsor

University Health Network, Toronto

Who can join

Adults 18 to 80, any sex, with Post-Surgical Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This randomized-controlled trial (RCT) will evaluate the effectiveness of a pain psychology intervention -- consisting of a hybrid of acceptance and commitment therapy (ACT) and clinical hypnosis intervention -- in reducing opioid consumption after major surgery. Consenting patients undergoing oncology surgeries at Toronto General Hospital (TGH) will be randomly assigned to one of two groups: (1) standard care or (2) standard care plus an ACT/clinical hypnosis intervention for pain management. The hypnosis intervention will be delivered via one session with a psychotherapist prior to surgery, one session with a psychotherapist after surgery, and the provision of audio recordings to guide patients in practicing self-hypnosis. The pain psychology intervention is targeted at reducing pain, as well as pain-related anxiety, distress, sleep disturbance, and functional impairment. The primary goal of the pain psychology intervention is to help patients to feel more comfortable while using less opioid medication in the week after surgery.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

A Randomized Controlled Trial of Clinical Hypnosis as an Opioid-Sparing Adjunct Treatment for Pain Relief in Adults Undergoing Major Oncologic Surgery.
Rosenbloom BN, Slepian PM, Azam MA, Aternali A, et al · · 2024 · cited 8× · PMID 38196969 · DOI 10.2147/jpr.s424639
Effects of perioperative clinical hypnosis on heart rate variability in patients undergoing oncologic surgery: secondary outcomes of a randomized controlled trial.
Azam MA, Weinrib AZ, Slepian PM, Rosenbloom BN, et al · · 2024 · cited 6× · PMID 38524266 · DOI 10.3389/fpain.2024.1354015

Verify or expand the search:

Other trials of Clinical Hypnosis

Trials testing the same drug.

NCT06095687 — Mind-body Therapies for Injury-related Pain Management in Elite Athletes · NA · withdrawn
NCT03809195 — Clinical Hypnosis in Pediatric Crohn's Disease · NA · completed

Other University Health Network, Toronto trials

Trials by the same sponsor.

NCT06831032 — Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response · NA · recruiting
NCT06634056 — Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients U · Phase 2 · not yet recruiting
NCT06836726 — Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resis · Phase 2 · not yet recruiting
NCT07515651 — Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas · Phase 2 · not yet recruiting
NCT07509450 — Fecal Microbiota Transplantation in Patients Undergoing Chimeric Antigen Receptor T-cell Therapy and Allogeneic Stem Cel · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03730350 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Health Network, Toronto
Last refreshed: 7 December 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03730350.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing