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NCT03728101
Drug Interaction Study of Simvastatin and Dabigatran
Phase 1 trial testing Simvastatin, Dabigatran Etexilate in Healthy in 12 participants. Completed in 15 December 2018.
15 December 2018
Quick facts
| Lead sponsor | Korea University Guro Hospital |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Design | sequential |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 12 |
| Start date | 16 November 2018 |
| Primary completion | 15 December 2018 |
| Estimated completion | 15 December 2018 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Simvastatin, Dabigatran Etexilate — full drug profile →
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
Korea University Guro Hospital
Who can join
Adults 19 to 50, male only, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the study is to evaluate the effect of simvastatin on the pharmacokinetics and pharmacodynamics of dabigatran in healthy male adults
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of Simvastatin on Pharmacokinetics and Anticoagulant Effects of Dabigatran in Healthy Subjects.
Chung H, Kim JM, Park JW, Noh J, et al · · 2023 · cited 3× · PMID 36986464 · DOI 10.3390/ph16030364
Verify or expand the search:
- PubMed search for NCT03728101
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03728101 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Korea University Guro Hospital
- Last refreshed: 12 March 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03728101.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing