NCT03727958: SIMULTANEOUS

Simultaneous Coronary Artery Evaluation and Lung Cancer CT Screening

Status unknown NA Last updated 1 November 2018

What this trial tests

NA trial testing Lung and coronary CT assessment in HEAVY SMOKING in 100 participants. Status unknown.

Timeline

1 November 2018

Primary endpoint
31 December 2018

31 December 2018

Quick facts

Lead sponsor	University of Roma La Sapienza
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	diagnostic
Enrollment	100
Start date	1 November 2018
Primary completion	31 December 2018
Estimated completion	31 December 2018

Drugs / interventions tested

• Lung and coronary CT assessment
• Coronary CT assessment

Conditions studied

• HEAVY SMOKING — all drugs for HEAVY SMOKING →

Sponsor

University of Roma La Sapienza

Who can join

40 and older, any sex, with HEAVY SMOKING. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiac computed tomography (CT) is often performed in patients who are at high risk for lung cancer in whom screening is currently recommended. This pilot randomized study will test the feasibility, safety and diagnostic ability of a novel ultra-low-dose CT protocol that allows concomitant coronary artery evaluation and lung screening. Current or former heavy smoker subjects with suspected or known coronary artery disease will be randomized to undergo CT assessment of either thoracic area only or both coronary arteries and thoracic area. Primary end-points will be the effective contrast and radiation doses.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Concomitant screening of coronary artery disease and lung cancer with a new ultrafast-low-dose Computed Tomography protocol: A pilot randomised trial.
   Gaudio C, Tanzilli A, Mei M, Moretti A, et al · · 2019 · cited 7× · PMID 31554878 · DOI 10.1038/s41598-019-50407-6