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NCT03726528: OCTOPUS
Optimized Characterization of Takotsubo Syndrome by Obtaining Pressure Volume Loops
NA trial testing Measurements of left ventricular pressure and volume in Takotsubo Syndrome in 25 participants. Completed in 7 October 2022.
7 October 2022
Quick facts
| Lead sponsor | University of Luebeck |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 25 |
| Start date | 1 September 2017 |
| Primary completion | 7 October 2022 |
| Estimated completion | 7 October 2022 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Measurements of left ventricular pressure and volume
Conditions studied
- Takotsubo Syndrome — all drugs for Takotsubo Syndrome →
Sponsor
University of Luebeck
Who can join
18 and older, any sex, with Takotsubo Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Aim of this prospective study is to assess the pathophysiology of Takotsubo Syndrome by obtaining pressure volume loops with conductance catheters, which allows detailed conclusions regarding systolic and diastolic hemondynamics and subsequently regarding potential underlying mechanisms
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Hemodynamic Assessment in Takotsubo Syndrome.
Stiermaier T, Reil JC, Sequeira V, Rawish E, et al · · 2023 · cited 17× · PMID 37197841 · DOI 10.1016/j.jacc.2023.03.398 -
Regional mechanical dyssynchrony and shortened systole are present in people with Takotsubo syndrome.
Reil JC, Sequeira V, Reil GH, Steendijk P, et al · · 2024 · PMID 39487225 · DOI 10.1038/s43856-024-00641-5
Verify or expand the search:
- PubMed search for NCT03726528
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Takotsubo Syndrome
Currently open trials in the same condition.
- NCT06954103 — Mechanisms And Prognosis of Stroke-Heart Syndrome · recruiting
- NCT06643949 — Italian Multicenter Observational Registry on Takostubo Syndrome · active not recruiting
Other University of Luebeck trials
Trials by the same sponsor.
- NCT06598280 — Same-Day Discharge Versus Overnight Stay Following Pulmonary Vein Isolation for Atrial Fibrillation · NA · recruiting
- NCT06493994 — Myval TransAXillary Transcatheter Aortic Valve Replacement Multicenter Clinical Registry · recruiting
- NCT05846412 — Treatment of Functional Mitral Regurgitation in Patients With Atrial Fibrillation · NA · unknown
- NCT05710822 — QDOT Based PVI for Atrial Fibrillation Treatment - The peQasus Study · unknown
- NCT05563142 — Venous Vascular Closure System Versus Manual Compression Following Single Shot Device AF Ablation · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03726528 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Luebeck
- Last refreshed: 19 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03726528.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing