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NCT03726073: AICE
Acupoint Stimulation Improve Postoperative Delirium in Elderly Patients
NA trial testing Transcutaneous acupoint electrical acupoint stimulation(TEAS) and auricular acupressure in Postoperative Complications in 210 participants. Completed in 10 April 2020.
10 March 2020
Quick facts
| Lead sponsor | Air Force Military Medical University, China |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 210 |
| Start date | 17 April 2019 |
| Primary completion | 10 March 2020 |
| Estimated completion | 10 April 2020 |
| Sites | 1 location across China |
Drugs / interventions tested
- Transcutaneous acupoint electrical acupoint stimulation(TEAS) and auricular acupressure
- Usual care
Conditions studied
- Postoperative Complications — all drugs for Postoperative Complications →
- Postoperative Delirium — all drugs for Postoperative Delirium →
Sponsor
Air Force Military Medical University, China
Who can join
Adults 65 to 100, any sex, with Postoperative Complications or Postoperative Delirium. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative delirium is with increased incidence in elderly patients. Previous studies have shown that acupuncture related techniques could induce protection against brain ischemia and improve outcome after cerebral diseases. In this study the effect of transcutaneous electrical acupoint stimulation combined with auricular acupressure on postoperative delirium will be evaluated.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Transcutaneous Electrical Acupoint Stimulation Combined With Auricular Acupressure Reduces Postoperative Delirium Among Elderly Patients Following Major Abdominal Surgery: A Randomized Clinical Trial.
Fan Q, Lei C, Wang Y, Yu N, et al · · 2022 · cited 13× · PMID 35783617 · DOI 10.3389/fmed.2022.855296 -
Association Between Plasma Amyloid-Beta 42 Ratio and Postoperative Delirium in Elderly Patients Undergoing Major Abdominal Surgery: Secondary Analysis of a Randomized Controlled Trial.
Fan Q, Wang Y, Lu Z, Wang L, et al · · 2025 · cited 2× · PMID 40259659 · DOI 10.1002/brb3.70501
Verify or expand the search:
- PubMed search for NCT03726073
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Air Force Military Medical University, China trials
Trials by the same sponsor.
- NCT07535138 — Efficacy and Safety of CD19 CAR-γδ T Cells in the Treatment of Relapsed/Refractory Autoimmune Nephropathy · EARLY_PHASE1 · not yet recruiting
- NCT07454408 — Evaluation of the Outcome of Fecal Microbiota Transplantation · Phase 1, PHASE2 · not yet recruiting
- NCT07329660 — Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients · NA · not yet recruiting
- NCT07365345 — Frequency of Electrical Acupoint Stimulation on Hypotension in TAVR Patients · NA · recruiting
- NCT07338448 — Electrical Acupoint Stimulation on Gastric Reflux During I-gel Ventilation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03726073 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Air Force Military Medical University, China
- Last refreshed: 26 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03726073.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing