Who is sponsoring NCT03725020?

NCT03725020 is sponsored by Malmö University.

What drugs are being tested in NCT03725020?

Interventions in NCT03725020: Fluoride varnish.

What condition does NCT03725020 study?

NCT03725020 studies Orthodontic Appliance Complication.

Is NCT03725020 still recruiting?

NCT03725020 is currently status unknown. Last updated 6 November 2018.

Last reviewed 2018-11-06 · How we verify

NCT03725020

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of a Novel Fluoride Varnish in Preventing WSL During/After Treatment With Fixed Orthodontic Appliances

Status unknown NA Last updated 6 November 2018

What this trial tests

NA trial testing Fluoride varnish in Orthodontic Appliance Complication in 180 participants. Status unknown.

Timeline

1 June 2014

Primary endpoint
31 December 2018

31 December 2019

Quick facts

Lead sponsor	Malmö University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	180
Start date	1 June 2014
Primary completion	31 December 2018
Estimated completion	31 December 2019

Drugs / interventions tested

Fluoride varnish

Conditions studied

Orthodontic Appliance Complication — all drugs for Orthodontic Appliance Complication →

Sponsor

Malmö University

Who can join

Adults 12 to 18, any sex, with Orthodontic Appliance Complication. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the present study is to evaluate the efficacy of a novel fluoride varnish (NFV) in preventing white spot lesion development in adolescents during and after treatment with fixed orthodontic appliances.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Fluoride varnish for the prevention of white spot lesions during orthodontic treatment with fixed appliances: a randomized controlled trial.
Sonesson M, Brechter A, Abdulraheem S, Lindman R, et al · · 2020 · cited 43× · PMID 31197364 · DOI 10.1093/ejo/cjz045
Fluoride varnish for white spot lesion prevention during orthodontic treatment: results of a randomized controlled trial 1 year after debonding.
Sonesson M, Brechter A, Lindman R, Abdulraheem S, et al · · 2021 · cited 13× · PMID 33009565 · DOI 10.1093/ejo/cjaa055

Verify or expand the search:

Other trials of Fluoride varnish

Trials testing the same drug.

NCT07141576 — Comparative Efficacy of Laser Systems and Fluoride in Managing Dentinal Hypersensitivity: RCT · NA · not yet recruiting
NCT07063433 — Effect of Gluma and Bioactive Glass Desensitizers in Treatment of Dentin Hypersensitivity in Cervical Non-Carious Lesion · NA · completed
NCT06797882 — Preventive Effects of Silver Diamine Fluoride on Early Enamel Caries · Phase 2 · not yet recruiting
NCT05969756 — Early Treatments for Preventing Occlusal Caries Lesions · NA · active not recruiting
NCT05960110 — Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexico · Phase 3 · unknown

Other recruiting trials for Orthodontic Appliance Complication

Currently open trials in the same condition.

NCT06944860 — Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Printed Twin Bl · NA · recruiting
NCT06573996 — The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain · NA · recruiting
NCT06502886 — Evaluation of The Stability of Orthodontic Treatment After First Premolar Extraction Using Combined Retention Protocol · NA · recruiting
NCT05733676 — Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment · NA · recruiting

Other Malmö University trials

Trials by the same sponsor.

NCT07390019 — Families Experiencing Cancer - Support to Prevent Cancer-related Illness · NA · not yet recruiting
NCT07344909 — Burning Mouth Syndrome: Effects of Occlusal Splint Therapy · NA · not yet recruiting
NCT07095101 — ePROPP - eHealth for Preventing and Reducing Orofacial Pain in the Population · NA · not yet recruiting
NCT07266701 — The General Aim is to Implement Clinical Assessment of Overload by Voluntary Bite Force Registration to Enable Future Si · enrolling by invitation
NCT06833034 — Comparing a Novel Closed Exposure Technique to a Conventional Method for Palatally Impacted Maxillary Canines · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03725020 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Malmö University
Last refreshed: 6 November 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03725020.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing